{"id":2225,"date":"2020-11-05T00:36:54","date_gmt":"2020-11-05T00:36:54","guid":{"rendered":"\/\/smallcapscn.x5view.co\/?p=2225"},"modified":"2023-08-29T17:47:34","modified_gmt":"2023-08-29T17:47:34","slug":"incannex-lead-drug-candidate-stronger-anti-inflammatory-cbd-preclinical-studies","status":"publish","type":"post","link":"https:\/\/smallcapscn.x5view.co\/?p=2225","title":{"rendered":"Incannex\u5019\u9009\u5148\u5bfc\u836f\u5728\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u8868\u73b0\u51fa\u6bd4CBD\u66f4\u5f3a\u7684\u6297\u708e\u4f5c\u7528"},"content":{"rendered":"

\u4e34\u5e8a\u9636\u6bb5\u5927\u9ebb\u7d20\u5f00\u53d1\u516c\u53f8Incannex Healthcare (ASX: IHL)<\/a>\u5728\u5176\u5148\u5bfc\u836f\u7269IHL- 675A\u5bf9\u8d25\u8840\u75c7\u76f8\u5173\u7684\u6025\u6027\u547c\u5438\u7a98\u8feb\u7efc\u5408\u5f81 (SAARDS)\u6297\u708e\u4f5c\u7528\u7684\u4e34\u5e8a\u524d\u4f53\u5916\u7814\u7a76\u4e2d\u83b7\u5f97\u4e86\u79ef\u6781\u7684\u7ed3\u679c\u3002<\/p>\n

\u4e0d\u540c\u56fa\u5b9a\u5242\u91cf\u7684IHL-675A\u7684\u4e24\u79cd\u5173\u952e\u6210\u5206\u2014\u2014\u5927\u9ebb\u4e8c\u915a(CBD)\u548c\u7f9f\u57fa\u6c2f\u55b9(HCQ)\u2014\u2014\u88ab\u7528\u4e8e\u7814\u7a76\uff0c\u4ee5\u8bc4\u4f30\u8be5\u836f\u7269\u7684\u6297\u708e\u53cd\u5e94\u3002\u672c\u5b9e\u9a8c\u663e\u793a\u8be5\u8054\u5408\u836f\u7269\u5bf9\u6240\u8bc4\u4f30\u7684\u708e\u75c7\u751f\u7269\u6807\u5fd7\u7269(\u7ec6\u80de\u56e0\u5b50)\u7684\u6291\u5236\u4f5c\u7528\u5927\u4e8eCBD\u7684\u500d\u6570\u3002<\/p>\n

\u8bd5\u9a8c\u65b9\u6cd5<\/h2>\n

\u8be5\u8bd5\u9a8c\u6d89\u53ca\u4eba\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de(PBMCs)\u7528\u7ec6\u83cc\u8102\u591a\u7cd6(LPS)\u523a\u6fc0\uff0c\u7136\u540e\u7528\u4e00\u7cfb\u5217CBD\u548cHCQ\u6d53\u5ea6\u5b75\u80b2\u3002<\/p>\n

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\u7ec6\u80de\u56e0\u5b50\u6291\u5236<\/h2>\n

IHL-675A\u5728\u7ed9\u836f24\u5c0f\u65f6\u540e\u8868\u73b0\u51fa\u6bd4\u7ec6\u80de\u56e0\u5b50\u6291\u5236CBD\u7684\u6548\u679c\u597d109%\u5230767%\u3002\u540c\u65f6\uff0cCBD-HCQ\u8054\u5408\u5242\u91cf\u6bd4\u9884\u6d4b\u7684\u7ec6\u80de\u56e0\u5b50\u6291\u5236\u6548\u679c\u597d87% ~ 767%\u3002<\/p>\n

Incannex\u8463\u4e8b\u603b\u7ecf\u7406\u517c\u9996\u5e2d\u6267\u884c\u5b98Joel Latham\u8868\u793a\uff0cCBD\u548cHCQ\u201c\u534f\u540c\u4f5c\u7528\u201d\u6291\u5236\u708e\u75c7\u7ec6\u80de\u56e0\u5b50\u7684\u4ea7\u751f\u3002<\/p>\n

\"{%ALT_TEXT%}\"
\u89c2\u5bdf\u523024\u5c0f\u65f6\u540eCBD + HCQ (IHL-675A)\u5bf9IL-6\u7ec6\u80de\u56e0\u5b50\u91ca\u653e\u7684\u6291\u5236\u8d85\u8fc7\u9884\u6d4b\u503c407%\u3002<\/figcaption><\/figure>\n

Incannex\u7279\u522b\u63d0\u4f9b\u4e86IHL-675A\u5bf9IL-6\u5f71\u54cd\u7684\u5b9e\u9a8c\u6570\u636e\uff0cIL-6\u662f\u4e00\u79cd\u7ec6\u80de\u56e0\u5b50\uff0c\u5728COVID-19\u5371\u673a\u671f\u95f4\u4f5c\u4e3a\u751f\u7269\u6807\u5fd7\u7269\u53d7\u5230\u4e86\u5a92\u4f53\u7684\u5173\u6ce8\u3002<\/p>\n

\u6269\u5927\u4e34\u65f6\u4e13\u5229<\/h2>\n

Incannex\u516c\u53f8\u5df2\u7ecf\u5bfb\u6c42CBD-HCQ\u8054\u5408\u6cbb\u7597SAARDS\u7684\u4e13\u5229\u4fdd\u62a4\uff0c\u56e0\u4e3aSAARDS\u662f\u4e00\u79cd\u5bf9\u611f\u67d3\u7684\u9ad8\u5ea6\u708e\u75c7\u53cd\u5e94\uff0c\u662f\u611f\u67d3\u75ab\u60c5\u75c5\u6bd2\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u3002<\/p>\n

\u7136\u800c\uff0c\u6d4b\u8bd5\u7684\u7ed3\u679c\u662f\uff0cIncannex\u5c06\u5176\u4e34\u65f6\u4e13\u5229\u4fdd\u62a4\u8303\u56f4\u6269\u5927\u5230\u4e00\u7cfb\u5217\u5176\u4ed6\u708e\u75c7\u6027\u75be\u75c5\uff0c\u8be5\u516c\u53f8\u8868\u793a\uff0c\u8fd9\u4e9b\u75be\u75c5\u5bf9\u516c\u53f8\u6765\u8bf4\u662f\u6f5c\u5728\u7684\u989d\u5916\u673a\u4f1a\u3002<\/p>\n

Latham\u5148\u751f\u8bf4Incannex\u516c\u53f8\u5c06\u5728\u672a\u6765\u7684\u7814\u7a76\u4e2d\u7ee7\u7eed\u8bc4\u4f30IHL-675A\u76f8\u5bf9\u4e8e\u4ec5\u4f7f\u7528cbd\u7684\u6cbb\u7597\u7684\u76ca\u5904\u3002<\/p>\n

\u201c\u4f5c\u4e3a\u4e00\u5bb6\u516c\u53f8\uff0c\u6211\u4eec\u7740\u624b\u83b7\u53d6\u8bc1\u636e\uff0c\u8bc1\u660e\u6211\u4eec\u7684\u4e13\u5229\u7ec4\u5408CBD\u548cHCQ\u5c06\u5728\u4e0e\u5355\u4e2a\u6210\u5206\u7684\u7ade\u4e89\u4e2d\u8868\u73b0\u51fa\u663e\u8457\u7684\u534f\u540c\u4f18\u52bf\u3002\u201d<\/p>\n

\u201c\u6211\u4eec\u4e0d\u4ec5\u6210\u529f\u5730\u505a\u5230\u4e86\u8fd9\u4e00\u70b9\uff0c\u800c\u4e14\u6211\u4eec\u5bf9IHL-675A\u8054\u5408\u836f\u7269\u6297\u708e\u6d3b\u6027\u7684\u9884\u671f\u4e5f\u5927\u5927\u8d85\u51fa\u4e86\u6211\u4eec\u7684\u9884\u671f\u3002\u201d\u8fd9\u53ef\u80fd\u610f\u5473\u7740IHL-675A\u662f\u6cbb\u7597\u708e\u75c7\u6027\u75be\u75c5\u7684CBD\u6cb9\u54c1\u66f4\u597d\u7684\u66ff\u4ee3\u54c1\uff0c\u4f46\u8fd8\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u68c0\u67e5\u3002\u201d<\/p>\n

\u5bf9SAARDS\u6ca1\u6709\u6ce8\u518c\u5904\u7406<\/h2>\n

SAARDS\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u547c\u5438\u8870\u7aed\uff0c\u6ca1\u6709\u6cbb\u7597\u53ef\u7528\u7684\u6279\u51c6\u7684\u836f\u7269\u4ee3\u7406\u3002<\/p>\n

\u8fd9\u79cd\u60c5\u51b5\u901a\u5e38\u5728\u91cd\u75c7\u76d1\u62a4\u75c5\u623f\u8fdb\u884c\u6cbb\u7597\uff0c\u4f7f\u7528\u673a\u68b0\u901a\u6c14\u548c\u8865\u5145\u6c27\u6c14\u3002<\/p>\n

\u673a\u68b0\u901a\u6c14\u901a\u5e38\u901a\u8fc7\u4e00\u6839\u56fa\u5b9a\u5728\u6c14\u9053\u4e2d\u7684\u786c\u7ba1\u8fdb\u5165\u53e3\u8154\uff0c\u6216\u5728\u9700\u8981\u957f\u65f6\u95f4\u901a\u6c14\u65f6\u901a\u8fc7\u6c14\u7ba1\u9020\u53e3\u672f\u8fdb\u884c\u3002<\/p>\n

\u6025\u6027\u547c\u5438\u7a98\u8feb\u7efc\u5408\u5f81\u7684\u751f\u5b58\u7387\u56e0\u5e74\u9f84\u3001\u75be\u75c5\u7684\u6f5c\u5728\u75c5\u56e0\u3001\u5171\u75c5\u548c\u5176\u4ed6\u56e0\u7d20\u800c\u5f02\u3002<\/p>\n

\u4e00\u4e9b\u7814\u7a76\u4f30\u8ba1\u60a3\u8005\u7684\u6b7b\u4ea1\u7387\u572836%\u523052%\u4e4b\u95f4\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e34\u5e8a\u9636\u6bb5\u5927\u9ebb\u7d20\u5f00\u53d1\u516c\u53f8Incannex Healthcare (ASX: IHL)\u5728\u5176\u5148\u5bfc\u836f\u7269IHL- 675A\u5bf9\u8d25\u8840\u75c7\u76f8\u5173\u7684\u6025\u6027\u547c\u5438\u7a98\u8feb\u7efc\u5408\u5f81 (SAARDS)\u6297\u708e\u4f5c\u7528\u7684\u4e34\u5e8a\u524d\u4f53\u5916\u7814\u7a76\u4e2d\u83b7\u5f97\u4e86\u79ef\u6781\u7684\u7ed3\u679c\u3002 \u4e0d\u540c\u56fa\u5b9a\u5242\u91cf\u7684IHL-675A\u7684\u4e24\u79cd\u5173\u952e\u6210\u5206\u2014\u2014\u5927\u9ebb\u4e8c\u915a(CBD)\u548c\u7f9f\u57fa\u6c2f\u55b9(HCQ)\u2014\u2014\u88ab\u7528\u4e8e\u7814\u7a76\uff0c\u4ee5\u8bc4\u4f30\u8be5\u836f\u7269\u7684\u6297\u708e\u53cd\u5e94\u3002\u672c\u5b9e\u9a8c\u663e\u793a\u8be5\u8054\u5408\u836f\u7269\u5bf9\u6240\u8bc4\u4f30\u7684\u708e\u75c7\u751f\u7269\u6807\u5fd7\u7269(\u7ec6\u80de\u56e0\u5b50)\u7684\u6291\u5236\u4f5c\u7528\u5927\u4e8eCBD\u7684\u500d\u6570\u3002 \u8bd5\u9a8c\u65b9\u6cd5 \u8be5\u8bd5\u9a8c\u6d89\u53ca\u4eba\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de(PBMCs)\u7528\u7ec6\u83cc\u8102\u591a\u7cd6(LPS)\u523a\u6fc0\uff0c\u7136\u540e\u7528\u4e00\u7cfb\u5217CBD\u548cHCQ\u6d53\u5ea6\u5b75\u80b2\u3002 \u8fd9\u4e9b\u6210\u5206\u5206\u522b\u5355\u72ec\u548c\u8054\u5408\u4f7f\u7528\uff0c\u7136\u540e\u7528\u8102\u591a\u7cd6\u523a\u6fc0\u5f15\u8d77\u708e\u75c7\u53cd\u5e94\u300224\u5c0f\u65f6\u540e\uff0c\u901a\u8fc7\u6d4b\u91cf\u57f9\u517b\u57fa\u4e2d\u7ec6\u80de\u56e0\u5b50(\u708e\u75c7\u7ec6\u80de\u4fe1\u53f7\u86cb\u767d)\u7684\u6c34\u5e73\u6765\u8bc4\u4f30\u53cd\u5e94\u3002\u836f\u7269\u6cbb\u7597\u5f15\u8d77\u7684\u7ec6\u80de\u56e0\u5b50\u6c34\u5e73\u964d\u4f4e\u88ab\u8ba4\u4e3a\u662f\u6297\u708e\u6d3b\u6027\u7684\u8868\u73b0\u3002 \u7ec6\u80de\u56e0\u5b50\u6291\u5236 IHL-675A\u5728\u7ed9\u836f24\u5c0f\u65f6\u540e\u8868\u73b0\u51fa\u6bd4\u7ec6\u80de\u56e0\u5b50\u6291\u5236CBD\u7684\u6548\u679c\u597d109%\u5230767%\u3002\u540c\u65f6\uff0cCBD-HCQ\u8054\u5408\u5242\u91cf\u6bd4\u9884\u6d4b\u7684\u7ec6\u80de\u56e0\u5b50\u6291\u5236\u6548\u679c\u597d87% ~ 767%\u3002 Incannex\u8463\u4e8b\u603b\u7ecf\u7406\u517c\u9996\u5e2d\u6267\u884c\u5b98Joel Latham\u8868\u793a\uff0cCBD\u548cHCQ\u201c\u534f\u540c\u4f5c\u7528\u201d\u6291\u5236\u708e\u75c7\u7ec6\u80de\u56e0\u5b50\u7684\u4ea7\u751f\u3002 Incannex\u7279\u522b\u63d0\u4f9b\u4e86IHL-675A\u5bf9IL-6\u5f71\u54cd\u7684\u5b9e\u9a8c\u6570\u636e\uff0cIL-6\u662f\u4e00\u79cd\u7ec6\u80de\u56e0\u5b50\uff0c\u5728COVID-19\u5371\u673a\u671f\u95f4\u4f5c\u4e3a\u751f\u7269\u6807\u5fd7\u7269\u53d7\u5230\u4e86\u5a92\u4f53\u7684\u5173\u6ce8\u3002 \u6269\u5927\u4e34\u65f6\u4e13\u5229 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