{"id":3981,"date":"2021-10-13T02:48:28","date_gmt":"2021-10-13T02:48:28","guid":{"rendered":"\/\/smallcapscn.x5view.co\/?p=3981"},"modified":"2023-08-29T18:01:44","modified_gmt":"2023-08-29T18:01:44","slug":"prescient-therapeutics-unveils-new-data-validating-cancer-cell-therapy-technology","status":"publish","type":"post","link":"https:\/\/smallcapscn.x5view.co\/?p=3981","title":{"rendered":"Prescient Therapeutics\u516c\u5e03\u4e86\u9a8c\u8bc1\u764c\u7ec6\u80de\u6cbb\u7597\u6280\u672f\u7684\u65b0\u6570\u636e"},"content":{"rendered":"

\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u516c\u5e03\u4e86\u65b0\u7684\u6570\u636e\uff0c\u8bc1\u660e\u5176OmniCAR\u7ec6\u80de\u6cbb\u7597\u6280\u672f\u80fd\u591f\u6740\u6b7b\u591a\u79cd\u764c\u7ec6\u80de\u3002<\/p>\n

\u672c\u5468\uff0c\u8be5\u516c\u53f8\u5728\u7f8e\u56fd\u52a0\u5dde\u7684\u7ec6\u80de\u6cbb\u7597\u4f1a\u8bae\u4e0a\u5c55\u793a\u4e86\u8fd9\u4e00\u4e34\u5e8a\u524d\u6570\u636e\uff0c\u8be5\u4f1a\u8bae\u88ab\u79f0\u4e3a\u201cMesa\u7ec6\u80de\u548c\u57fa\u56e0\u4f1a\u8bae\u201d\u3002<\/p>\n

\u5728\u4f1a\u8bae\u62a5\u544a\u4e2d\uff0cPrescient\u8bf4\uff0cOmniCAR\u7684\u5173\u952e\u5c5e\u6027\u5305\u62ec\u663e\u793a\u80bf\u7624\u6740\u4f24\u6d3b\u6027\u548c\u9ad8\u6548\u529b\u7684\u5242\u91cf\u53cd\u5e94\u5173\u7cfb\uff0c\u8bc1\u660e\u4e86OmniCAR- t\u7ec6\u80de\u7684\u91cd\u65b0\u88c5\u5907\uff0c\u4ee5\u53ca\u5c06OmniCAR- t\u7ec6\u80de\u4ece\u4e00\u79cd\u764c\u75c7\u6297\u539f\u91cd\u65b0\u5b9a\u5411\u5230\u53e6\u4e00\u79cd\u764c\u75c7\u6297\u539f\u7684\u987a\u5e8f\u88c5\u5907\u3002<\/p>\n

\u8fd9\u9879\u6700\u65b0\u7684\u7814\u7a76\u662f\u4e0e\u58a8\u5c14\u672c\u7684Peter MacCallum\u764c\u75c7\u4e2d\u5fc3\u5408\u4f5c\u8fdb\u884c\u7684\uff0c\u7ef4\u591a\u5229\u4e9a\u548c\u6709\u5148\u89c1\u7684\u79d1\u5b66\u4e8b\u52a1\u4e3b\u4efbDr Rebecca Lim\u8bf4\uff0c\u6570\u636e\u4ecd\u7136\u662f\u201c\u975e\u5e38\u79ef\u6781\u7684\u201d\u3002<\/p>\n

\u201c\u6211\u4eec\u6700\u8fd1\u7684\u7814\u7a76\u8868\u660e\uff0cOmniCAR-T\u7ec6\u80de\u4e00\u65e6\u6b66\u88c5\u8d77\u6765\uff0c\u5c31\u5f00\u59cb\u5728\u4f53\u5916\u5bf9\u80bf\u7624\u7ec6\u80de\u8fdb\u884c\u6297\u539f\u5b9a\u5411\u6740\u4f24\u3002<\/p>\n

\u5979\u8865\u5145\u8bf4:\u201c\u7814\u7a76\u5c0f\u7ec4\u8fd8\u8868\u660e\uff0cOmniCAR-T\u7ec6\u80de\u53ef\u4ee5\u91cd\u65b0\u6b66\u88c5\uff0c\u5e76\u5728\u4e0d\u4e27\u5931\u7ec6\u80de\u6bd2\u6027\u7684\u60c5\u51b5\u4e0b\u7ee7\u7eed\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u3002\u201d<\/p>\n

Dr Lim\u5c06\u65e9\u671f\u7684\u80dc\u5229\u63cf\u8ff0\u4e3a\u201c\u975e\u5e38\u4ee4\u4eba\u9f13\u821e\u201d\u3002<\/p>\n

\u201c\u4ee4\u4eba\u5174\u594b\u7684\u662f\uff0c\u6211\u4eec\u7b2c\u4e00\u6b21\u770b\u5230\u4e86OmniCAR\u7cfb\u7edf\u7684\u5b9e\u65f6\u2018\u5207\u6362\u6027\u2019\uff0c\u901a\u8fc7\u6dfb\u52a0\u4e0d\u540c\u7684\u7ed3\u5408\u5242\uff0cOmniCAR- T\u7ec6\u80de\u7684\u80bf\u7624\u6740\u4f24\u80fd\u529b\u53ef\u4ee5\u88ab\u91cd\u5b9a\u5411\u5230\u4e0d\u540c\u7684\u6297\u539f\u3002\u201d<\/p>\n

\u201c\u6211\u4eec\u671f\u5f85\u4e0b\u4e00\u9636\u6bb5\u7684\u4e34\u5e8a\u524d\u6d4b\u8bd5\uff0c\u5728\u90a3\u91ccOmniCAR\u6280\u672f\u5c06\u4f7f\u7528\u9ec4\u91d1\u6807\u51c6\u7684\u764c\u75c7\u6a21\u578b\u8fdb\u884c\u6d4b\u8bd5\u3002\u201d<\/p>\n

\u7ec6\u80de\u80fd\u591f\u88ab\u91cd\u5b9a\u5411\u5230\u4e0d\u540c\u7684\u6297\u539f\u9776\u70b9<\/h2>\n

Prescient\u6b63\u5728\u5f00\u53d1\u4e0b\u4e00\u4ee3CAR-T\u7597\u6cd5\u7684OmniCAR\u9879\u76ee\uff0c\u7528\u4e8e\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5(AML)\uff0c her2 +\u5b9e\u4f53\u80bf\u7624\uff0c\u5305\u62ec\u4e73\u817a\u764c\u3001\u5375\u5de2\u764c\u548c\u80c3\u764c\uff0c\u4ee5\u53ca\u88ab\u79f0\u4e3a\u591a\u5f62\u6027\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624(GBM)\u7684\u8111\u764c\u3002<\/p>\n

\u7279\u522b\u662f\uff0cGBM\u7684\u7279\u70b9\u662f\u6297\u539f\u5f02\u8d28\u6027\u548c\u5feb\u901f\u7a81\u53d8\uff0c\u8fd9\u9a71\u52a8\u4e86\u764c\u75c7\u7684\u5feb\u901f\u8fdb\u5c55\u3002\u8fd9\u4e9b\u7279\u5f81\u4f7fCAR-T\u548c\u5176\u4ed6\u7597\u6cd5\u5177\u6709\u6311\u6218\u6027\uff0c\u56e0\u4e3a\u5b83\u4eec\u4f9d\u8d56\u4e8e\u5355\u4e00\u6297\u539f\u9776\u5411\u3002<\/p>\n

Prescient\u6b63\u8bd5\u56fe\u901a\u8fc7OmniCAR\u7684\u53d1\u5c55\u6765\u514b\u670d\u8fd9\u4e9b\u9650\u5236\uff0c\u4f7f\u591a\u6297\u539f\u9776\u5411\u6210\u4e3a\u53ef\u80fd\u3002<\/p>\n

\u5728\u4e00\u9879\u65b0\u7684\u5b9e\u9a8c\u4e2d\uff0cOmniCAR\u5bf9\u8868\u8fbe\u6297\u539fHer2\u6216EGFRviii\u7684GBM\u7ec6\u80de\u5171\u57f9\u517b\u8fdb\u884c\u4e86\u6d4b\u8bd5\u3002\u9884\u88c5\u5907EGFRviii\u7ed3\u5408\u7269\u7684OmniCAR-T\u7ec6\u80de\u5bf9\u8868\u8fbeEGFRviii\u7684GBM\u7ec6\u80de\u8868\u73b0\u51fa\u5feb\u901f\u7684\u7ec6\u80de\u6bd2\u6027\u3002<\/p>\n

\u4e0e\u6b64\u540c\u65f6\uff0c\u968f\u540e\u7ed9\u836fHer2\u7ed3\u5408\u7269\u663e\u793a\u4e86\u643a\u5e26Her2\u7684OmniCAR-T\u7ec6\u80de\u7684\u5feb\u901f\u5207\u6362\uff0c\u5e76\u76f8\u5e94\u7684\u5bf9Her2 + GBM\u7ec6\u80de\u7684\u5feb\u901f\u7ec6\u80de\u6bd2\u6027\u3002<\/p>\n

\u6839\u636ePrescient\uff0c\u8fd9\u8868\u660eOmniCAR\u7ec6\u80de\u53ef\u4ee5\u91cd\u5b9a\u5411\u5230\u4e0d\u540c\u7684\u6297\u539f\u9776\u70b9\uff0c\u901a\u8fc7\u4e0d\u540c\u7684SpyTagged\u7c98\u5408\u5242\uff0c\u800c\u4e0d\u9700\u8981\u65b0\u7684\u7ec6\u80de\u3002\u5728\u6bcf\u4e2a\u6848\u4f8b\u4e2d\uff0cOmniCAR\u90fd\u8868\u73b0\u51fa\u4e86\u9ad8\u5ea6\u9776\u5411\u7684\u80bf\u7624\u6740\u4f24\u80fd\u529b\u3002<\/p>\n

Prescient\u8ba4\u4e3a\uff0c\u8fd9\u4e00\u9ad8\u5ea6\u65b0\u9896\u7684\u7279\u5f81\u4e5f\u5c06\u5728AML\u7684OmniCAR\u53d1\u5c55\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002AML\u662f\u53e6\u4e00\u79cd\u4ee5\u9ad8\u6297\u539f\u5f02\u8d28\u6027\u3001\u5feb\u901f\u7a81\u53d8\u548c\u5feb\u901f\u75be\u75c5\u8fdb\u5c55\u4e3a\u7279\u5f81\u7684\u764c\u75c7\u3002<\/p>\n

\u7136\u800c\u8981\u53d1\u73b0OmniCAR\u6280\u672f\u7684\u771f\u6b63\u5c40\u9650\u6027<\/h2>\n

\u6709\u5148\u89c1\u4e4b\u660e\u7684\u8463\u4e8b\u603b\u7ecf\u7406\u517c\u9996\u5e2d\u6267\u884c\u5b98Steven Yatomi-Clarke\u8bf4\uff0c\u5927\u91cf\u5de5\u4f5c\u5982\u6b64\u8fc5\u901f\u548c\u6210\u529f\u5730\u5b8c\u6210\uff0c\u662f\u56e2\u961f\u548cPeter MacCallum\u764c\u75c7\u4e2d\u5fc3\u7684\u5408\u4f5c\u8005\u7684\u529f\u52b3\u3002<\/p>\n

\u4ed6\u8bf4:\u201c\u91cd\u8981\u7684\u662f\uff0c\u8fd9\u4e9b\u6d4b\u8bd5\u751a\u81f3\u90fd\u6ca1\u6709\u7ecf\u8fc7\u4f18\u5316\uff0c\u6240\u4ee5\u6211\u4eec\u8fd8\u6ca1\u6709\u770b\u5230\u8fd9\u9879\u6280\u672f\u7684\u771f\u6b63\u5c40\u9650\u6027\u3002\u201d<\/p>\n

\u201cOmniCAR\u88ab\u8bc1\u660e\u662f\u4e00\u4e2a\u53ef\u9884\u6d4b\u548c\u5f3a\u5927\u7684\u7cfb\u7edf\u3002\u968f\u7740\u9879\u76ee\u7684\u8fdb\u5c55\uff0c\u6211\u4eec\u671f\u5f85\u5206\u4eab\u6700\u65b0\u60c5\u51b5\u3002\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u516c\u5e03\u4e86\u65b0\u7684\u6570\u636e\uff0c\u8bc1\u660e\u5176OmniCAR\u7ec6\u80de\u6cbb\u7597\u6280\u672f\u80fd\u591f\u6740\u6b7b\u591a\u79cd\u764c\u7ec6\u80de\u3002 \u672c\u5468\uff0c\u8be5\u516c\u53f8\u5728\u7f8e\u56fd\u52a0\u5dde\u7684\u7ec6\u80de\u6cbb\u7597\u4f1a\u8bae\u4e0a\u5c55\u793a\u4e86\u8fd9\u4e00\u4e34\u5e8a\u524d\u6570\u636e\uff0c\u8be5\u4f1a\u8bae\u88ab\u79f0\u4e3a\u201cMesa\u7ec6\u80de\u548c\u57fa\u56e0\u4f1a\u8bae\u201d\u3002 \u5728\u4f1a\u8bae\u62a5\u544a\u4e2d\uff0cPrescient\u8bf4\uff0cOmniCAR\u7684\u5173\u952e\u5c5e\u6027\u5305\u62ec\u663e\u793a\u80bf\u7624\u6740\u4f24\u6d3b\u6027\u548c\u9ad8\u6548\u529b\u7684\u5242\u91cf\u53cd\u5e94\u5173\u7cfb\uff0c\u8bc1\u660e\u4e86OmniCAR- t\u7ec6\u80de\u7684\u91cd\u65b0\u88c5\u5907\uff0c\u4ee5\u53ca\u5c06OmniCAR- t\u7ec6\u80de\u4ece\u4e00\u79cd\u764c\u75c7\u6297\u539f\u91cd\u65b0\u5b9a\u5411\u5230\u53e6\u4e00\u79cd\u764c\u75c7\u6297\u539f\u7684\u987a\u5e8f\u88c5\u5907\u3002 \u8fd9\u9879\u6700\u65b0\u7684\u7814\u7a76\u662f\u4e0e\u58a8\u5c14\u672c\u7684Peter MacCallum\u764c\u75c7\u4e2d\u5fc3\u5408\u4f5c\u8fdb\u884c\u7684\uff0c\u7ef4\u591a\u5229\u4e9a\u548c\u6709\u5148\u89c1\u7684\u79d1\u5b66\u4e8b\u52a1\u4e3b\u4efbDr Rebecca Lim\u8bf4\uff0c\u6570\u636e\u4ecd\u7136\u662f\u201c\u975e\u5e38\u79ef\u6781\u7684\u201d\u3002 \u201c\u6211\u4eec\u6700\u8fd1\u7684\u7814\u7a76\u8868\u660e\uff0cOmniCAR-T\u7ec6\u80de\u4e00\u65e6\u6b66\u88c5\u8d77\u6765\uff0c\u5c31\u5f00\u59cb\u5728\u4f53\u5916\u5bf9\u80bf\u7624\u7ec6\u80de\u8fdb\u884c\u6297\u539f\u5b9a\u5411\u6740\u4f24\u3002 \u5979\u8865\u5145\u8bf4:\u201c\u7814\u7a76\u5c0f\u7ec4\u8fd8\u8868\u660e\uff0cOmniCAR-T\u7ec6\u80de\u53ef\u4ee5\u91cd\u65b0\u6b66\u88c5\uff0c\u5e76\u5728\u4e0d\u4e27\u5931\u7ec6\u80de\u6bd2\u6027\u7684\u60c5\u51b5\u4e0b\u7ee7\u7eed\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u3002\u201d Dr Lim\u5c06\u65e9\u671f\u7684\u80dc\u5229\u63cf\u8ff0\u4e3a\u201c\u975e\u5e38\u4ee4\u4eba\u9f13\u821e\u201d\u3002 \u201c\u4ee4\u4eba\u5174\u594b\u7684\u662f\uff0c\u6211\u4eec\u7b2c\u4e00\u6b21\u770b\u5230\u4e86OmniCAR\u7cfb\u7edf\u7684\u5b9e\u65f6\u2018\u5207\u6362\u6027\u2019\uff0c\u901a\u8fc7\u6dfb\u52a0\u4e0d\u540c\u7684\u7ed3\u5408\u5242\uff0cOmniCAR- T\u7ec6\u80de\u7684\u80bf\u7624\u6740\u4f24\u80fd\u529b\u53ef\u4ee5\u88ab\u91cd\u5b9a\u5411\u5230\u4e0d\u540c\u7684\u6297\u539f\u3002\u201d 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