{"id":4319,"date":"2021-12-02T22:37:04","date_gmt":"2021-12-02T22:37:04","guid":{"rendered":"\/\/smallcapscn.x5view.co\/?p=4319"},"modified":"2023-08-29T18:01:41","modified_gmt":"2023-08-29T18:01:41","slug":"race-oncology-seeks-cash-advance-anti-cancer-heart-protection-drug","status":"publish","type":"post","link":"https:\/\/smallcapscn.x5view.co\/?p=4319","title":{"rendered":"Race Oncology\u5bfb\u6c42\u8d44\u91d1\u6765\u7814\u53d1\u6297\u764c\u548c\u5fc3\u810f\u4fdd\u62a4\u836f\u7269"},"content":{"rendered":"

\u7cbe\u51c6\u80bf\u7624\u5b66\u516c\u53f8Race Oncology (ASX: RAC)\u6b63\u5728\u5bfb\u6c42\u878d\u8d44\uff0c\u4ee5\u5b9e\u65bd\u5176\u6269\u5927\u7684\u4e1a\u52a1\u6218\u7565\uff0c\u5e76\u5728\u6700\u8fd1\u7684\u7a81\u7834\u6027\u53d1\u73b0\u540e\u63a8\u8fdb\u5176\u6297\u764c\u836f\u7269Zantrene\u7684\u4e34\u5e8a\u9879\u76ee\u3002<\/p>\n

\u8be5\u516c\u53f8\u5df2\u7ecf\u542f\u52a8\u4e86\u4e00\u9879\u80a1\u7968\u8d2d\u4e70\u8ba1\u5212\uff0c\u4ee5\u7b79\u96c6\u9ad8\u8fbe2970\u4e07\u6fb3\u5143\u7684\u8d44\u91d1\uff0c\u4ee5\u8d44\u52a9\u591a\u4e2a\u4e8c\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5e76\u6539\u8fdbZantrene\u7684\u914d\u65b9\uff0c\u5e76\u8fdb\u884c\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u548c\u5f00\u53d1\u3002<\/p>\n

Zantrene\u00ae(bisantrene dihydrochloride)\u662f\u4e00\u79cd\u5c0f\u5206\u5b50\u6297\u764c\u836f\u7269\uff0c\u5df2\u88ab\u8bc1\u660e\u662f\u4e00\u79cd\u4f4e\u5242\u91cf\u7684\u9ad8\u9776\u5411\u7cbe\u51c6\u80bf\u7624\u5236\u5242\u548c\u9ad8\u5242\u91cf\u7684\u5316\u7597\u836f\u7269\u3002<\/p>\n

\u5b83\u88ab\u9274\u5b9a\u4e3a\u4e00\u79cdFatso\/Fat Mass and Obesity Associated (FTO)\u86cb\u767d\u7684\u9ad8\u6548\u6291\u5236\u5242\uff0c\u8be5\u86cb\u767d\u7684\u8fc7\u8868\u8fbe\u5df2\u88ab\u8bc1\u660e\u662f\u591a\u79cd\u764c\u75c7\u7684\u57fa\u56e0\u9a71\u52a8\u56e0\u7d20\u3002<\/p>\n

\u79cd\u65cf\u80bf\u7624\u5b66\u6b63\u5728\u63a2\u7d22Zantrene\u4f5c\u4e3a\u9ed1\u8272\u7d20\u7624(\u76ae\u80a4\u764c)\u548c\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c(\u80be\u764c)\u7684\u65b0\u7597\u6cd5\uff0c\u8fd9\u4e24\u79cd\u80bf\u7624\u90fd\u662f\u5e38\u89c1\u7684FTO\u8fc7\u8868\u8fbe\u764c\u75c7\u3002<\/p>\n

\u5b83\u4e5f\u6709\u4ee4\u4eba\u4fe1\u670d\u7684\u4e34\u5e8a\u6570\u636e\uff0cZantrene\u4f5c\u4e3a\u4e00\u79cd\u5316\u7597\u836f\u7269\uff0c\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5(AML)\u76842\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002\u5728\u6b64\u4e4b\u524d\uff0c2020\u5e74\u4e00\u9879\u5c0f\u89c4\u6a21\u7684AML\u6982\u5ff5\u9a8c\u8bc12\u671f\u8bd5\u9a8c\u5728\u4e00\u4e2a\u96be\u4ee5\u6cbb\u7597\u7684\u60a3\u8005\u7ec4\u4e2d\u63d0\u4f9b\u4e8640%\u7684\u4e34\u5e8a\u7f13\u89e3\u7387\u3002<\/p>\n

\u5fc3\u810f\u4fdd\u62a4\u7684\u7a81\u7834\u6027\u53d1\u73b0<\/h2>\n

\u4e0a\u4e2a\u6708\uff0c\u8be5\u516c\u53f8\u5ba3\u5e03\u4e86\u5176\u4e34\u5e8a\u524d\u7814\u7a76\u7684\u4e00\u9879\u7a81\u7834\uff0c\u53d1\u73b0Zantrene\u4fdd\u62a4\u514d\u53d7\u84bd\u73af\u7c7b\u836f\u7269\u5f15\u8d77\u7684\u5fc3\u810f\u635f\u4f24\uff0c\u540c\u65f6\u4e0e\u84bd\u73af\u7c7b\u836f\u7269(\u5316\u7597\u836f\u7269)\u534f\u540c\u4f5c\u7528\uff0c\u63d0\u9ad8\u5176\u9776\u5411\u4e73\u817a\u764c\u7684\u80fd\u529b\u3002<\/p>\n

Race Oncology\u6253\u7b97\u8fdb\u4e00\u6b65\u8bc4\u4f30\u8fd9\u4e00\u91cd\u8981\u53d1\u73b0\uff0c\u5feb\u901f\u89c4\u52122022\u5e74\u9488\u5bf9\u84bd\u73af\u7c7b\u836f\u7269\u5f15\u8d77\u5fc3\u810f\u635f\u4f24\u9ad8\u98ce\u9669\u4e73\u817a\u764c\u60a3\u8005\u76842b\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\u7ebd\u5361\u65af\u5c14\u5927\u5b66(University of Newcastle)\u526f\u6559\u6388Aaron Sverdlov\u8bf4\uff0c\u7531\u4e8e\u533b\u7597\u4fdd\u5065\u4e2d\u9488\u5bf9\u7279\u5b9a\u75be\u75c5\u7684\u65b9\u6cd5\uff0c\u5728\u6b64\u4e4b\u524d\uff0c\u65e2\u65e0\u5fc3\u810f\u6bd2\u6027\u53c8\u5bf9\u5fc3\u810f\u6709\u4fdd\u62a4\u4f5c\u7528\u7684\u6f5c\u5728\u764c\u75c7\u7597\u6cd5\u7684\u6982\u5ff5\u8fd8\u6ca1\u6709\u5f97\u5230\u8bc4\u4f30\uff0c\u751a\u81f3\u6ca1\u6709\u88ab\u8003\u8651\u8fc7\u3002<\/p>\n

\u201c\u6211\u4eec\u7684\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u8d5e\u7279\u6797\u662f\u4e00\u79cd\u6709\u6548\u7684\u6297\u764c\u836f\u7269\uff0c\u53ef\u4ee5\u540c\u65f6\u4fdd\u62a4\u5fc3\u810f\u514d\u53d7\u963f\u9709\u7d20(\u4e00\u79cd\u6700\u5e38\u7528\u7684\u5316\u7597\u836f\u7269)\u7684\u6bd2\u6027\u5f71\u54cd\u3002\u201d<\/p>\n

\u201c\u8fd9\u662f\u7b2c\u4e00\u4e2a\u8bc1\u660e\u6709\u4e00\u79cd\u6cbb\u7597\u65b9\u6cd5\u65e2\u80fd\u6cbb\u7597\u764c\u75c7\u53c8\u80fd\u4fdd\u62a4\u5fc3\u810f\u7684\u8bc1\u636e\u3002\u201d<\/p>\n

Sverdlov\u6559\u6388\u8865\u5145\u8bf4:\u201c\u901a\u8fc7\u6539\u5584\u764c\u75c7\u6cbb\u7597\uff0c\u540c\u65f6\u9884\u9632\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u53d1\u5c55\uff0c\u5b83\u6709\u53ef\u80fd\u6539\u5584\u65e0\u6570\u764c\u75c7\u60a3\u8005\u548c\u5e78\u5b58\u8005\u7684\u5065\u5eb7\u7ed3\u679c\u3002\u201d<\/p>\n

\u79cd\u65cf\u80bf\u7624\u5b66\u9996\u5e2d\u79d1\u5b66\u5b98Daniel Tillett\u535a\u58eb\u5c06\u8fd9\u4e00\u7a81\u7834\u6027\u7684\u8fdb\u5c55\u63cf\u8ff0\u4e3a\u201c\u4e24\u5168\u5929\u4e0b\u201d\u7684\u7ed3\u679c\u3002<\/p>\n

\u4ed6\u8bf4:\u201c\u8003\u8651\u5230\u6bcf\u5e74\u6709\u6570\u767e\u4e07\u764c\u75c7\u60a3\u8005\u4f7f\u7528\u84bd\u73af\u7c7b\u836f\u7269\uff0c\u5f88\u96be\u5938\u5927\u8fd9\u4e00\u7a81\u7834\u7684\u4e34\u5e8a\u548c\u5546\u4e1a\u6f5c\u529b\u3002\u201d<\/p>\n

\u80a1\u4efd\u8d2d\u4e70\u8ba1\u5212\u57fa\u91d1<\/h2>\n

\u8be5\u80a1\u7968\u8d2d\u4e70\u8ba1\u5212\u4e8e11\u670823\u65e5\u5f00\u59cb\uff0c\u5411\u5408\u683c\u7684\u73b0\u6709\u80a1\u4e1c\u63d0\u4f9b\u4ee5\u6bcf\u80a13\u6fb3\u5143\u7684\u4ef7\u683c\u8d2d\u4e70\u81f3\u591a3\u4e07\u6fb3\u5143\u5df2\u5168\u989d\u652f\u4ed8\u7684\u80a1\u7968\u7684\u673a\u4f1a\u3002\u8fd9\u6bd4\u524d\u4e94\u4e2a\u4ea4\u6613\u65e5\u7684\u6210\u4ea4\u91cf\u52a0\u6743\u5e73\u5747\u4ef7\u683c\u4f4e\u4e8617.4%\u3002<\/p>\n

\u57fa\u91d1\u7684\u4f7f\u7528\u6570\u91cf\u5c06\u53d6\u51b3\u4e8e\u63d0\u51fa\u4f46\u5728\u4f18\u5148\u79e9\u5e8f,\u79cd\u65cf\u80bf\u7624\u5b66\u8868\u793a,800\u4e07\u6fb3\u5143\u5c06\u57fa\u91d11\/2 FTO\u56fa\u4f53\u80bf\u7624\u671f\u4e34\u5e8a\u8bd5\u9a8c,\u8fdb\u4e00\u6b65220\u4e07\u6fb3\u5143\u82b1\u8d39\u5728Zantrene\u6539\u8fdb\u914d\u65b9,100\u4e07\u6fb3\u5143\u7528\u4e8e\u4e34\u5e8a\u524dcardio-protection\u7814\u7a76\u548c800000\u6fb3\u5143\u7684\u53d1\u5c55\u65b0\u5206\u5b50\u3002<\/p>\n

\u5728\u4e2d\u95f4\u60c5\u51b5\u4e0b\uff0c\u6539\u8fdbZantrene\u914d\u65b9\u7684\u9884\u7b97\u5c06\u589e\u52a0\u5230260\u4e07\u6fb3\u5143\uff0c\u53e6\u5916750\u4e07\u6fb3\u5143\u5c06\u7528\u4e8e\u4e73\u817a\u764c\u60a3\u8005\u7684\u5fc3\u810f\u4fdd\u62a420\u4ebf\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n

\u5982\u679c\u5168\u90e8\u7b79\u96c6\u52302970\u4e07\u6fb3\u5143\uff0c\u4e8c\u671f\u9ad3\u5916(EMD)\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\/\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38(AML\/MDS)\u4e34\u5e8a\u8bd5\u9a8c\u4e5f\u5c06\u83b7\u5f97920\u4e07\u6fb3\u5143\u7684\u8d44\u52a9\uff0c\u53e6\u591660\u4e07\u6fb3\u5143\u5c06\u7528\u4e8e\u6539\u8fdbZantrene\u914d\u65b9\uff0c\u603b\u989d\u4e3a320\u4e07\u6fb3\u5143\u3002<\/p>\n

\u80a1\u7968\u8d2d\u4e70\u8ba1\u5212\u5c06\u4e8e12\u670817\u65e5\u7ed3\u675f\uff0c\u9884\u8ba1\u5c06\u4e8e12\u670821\u65e5\u516c\u5e03\u7ed3\u679c\u548c\u53d1\u884c\u65b0\u80a1\u3002\u8be5\u8981\u7ea6\u6ca1\u6709\u5305\u9500\u3002<\/p>\n

Race\u7684\u201c\u4e09\u5927\u652f\u67f1\u201d\u5546\u4e1a\u6218\u7565<\/h2>\n

Race Oncology\u6b63\u5728\u5bfb\u6c42Zantrene\u4e34\u5e8a\u5f00\u53d1\u7684\u201c\u4e09\u652f\u67f1\u201d\u6218\u7565\u3002<\/p>\n

\u7b2c\u4e00\u4e2a\u652f\u67f1\u662f\u6700\u5927\u5316\u76ee\u524d\u7684Zantrene\u914d\u65b9\uff0c\u5305\u62ecFTO\u6291\u5236\u3001\u5fc3\u810f\u4fdd\u62a4\u548cAML\u5546\u4e1a\u5316\u9014\u5f84\u3002<\/p>\n

\u7b2c\u4e8c\u4e2a\u652f\u67f1\u662f\u589e\u52a0Zantrene\u7684\u65b0\u914d\u65b9\u548c\u7528\u4e8efto\u9776\u5411\u5b9e\u4f53\u80bf\u7624\u7684\u77e5\u8bc6\u4ea7\u6743\u3002\u7b2c\u4e09\u4e2a\u652f\u67f1\u662f\u65b0\u7684\u5206\u5b50\u5f00\u53d1\uff0c\u53ef\u80fd\u6d89\u53ca\u5408\u4f5c\u548c\/\u6216\u6536\u8d2d\u3002<\/p>\n

Zantrene\u4f5c\u4e3a\u5fc3\u810f\u4fdd\u62a4\u836f\u7269\u7684\u5546\u673a<\/h2>\n

Race Oncology\u9996\u5e2d\u6267\u884c\u5b98\u517c\u8463\u4e8b\u603b\u7ecf\u7406Phil Lynch\u5728\u4e00\u6bb5\u89c6\u9891\u6f14\u793a\u4e2d\u8868\u793a\uff0cZantrene\u4f5c\u4e3a\u5fc3\u810f\u4fdd\u62a4\u5242\u7684\u5f00\u53d1\u201c\u6bcf\u5e74\u4e3a\u6570\u767e\u4e07\u764c\u75c7\u60a3\u8005\u5e26\u6765\u6f5c\u5728\u7684\u673a\u4f1a\u201d\uff0c\u56e0\u4e3a\u5b83\u53ef\u4ee5\u7528\u4e8e\u4f7f\u7528\u84bd\u73af\u7c7b\u836f\u7269\u7684\u5927\u591a\u6570\u60a3\u8005\u3002<\/p>\n

\u201c\u5728\u5546\u4e1a\u4e0a\uff0c\u6211\u4eec\u53ef\u4ee5\u72ec\u7acb\u9500\u552eZantrene\uff0c\u5b83\u53ef\u4ee5\u4e0e\u84bd\u73af\u7c7b\u836f\u7269\u8f85\u52a9\u4f7f\u7528\uff0c\u6211\u4eec\u53ef\u80fd\u6709\u5171\u540c\u914d\u65b9\u7684\u4ea7\u54c1\u548c\u89e3\u51b3\u65b9\u6848\uff0c\u6211\u4eec\u53ef\u4ee5\u6388\u6743\uff0c\u6216\u8005\u6211\u4eec\u53ef\u4ee5\u5408\u4f5c\u3002\u672a\u6765\u8fd8\u6709\u5927\u91cf\u7684\u673a\u4f1a\u6709\u5f85\u63a2\u7d22\u3002\u201d<\/p>\n

\u8482\u5229\u7279\u535a\u58eb\u8bf4\uff0c\u8fd9\u4e00\u7a81\u7834\u5bf9\u764c\u75c7\u60a3\u8005\u5c24\u5176\u91cd\u8981\uff0c\u56e0\u4e3a\u8fd9\u610f\u5473\u7740\u4ed6\u4eec\u53ef\u4ee5\u63a5\u53d7\u6700\u4f73\u7684\u5316\u7597\uff0c\u800c\u4e0d\u4f1a\u6709\u957f\u671f\u5f71\u54cd\u5fc3\u810f\u7684\u98ce\u9669\u3002<\/p>\n

\u4ed6\u8bf4:\u201c\u76ee\u524d\uff0c\u8bb8\u591a\u764c\u75c7\u60a3\u8005\u53ef\u80fd\u4f1a\u5f97\u5230\u6b21\u4f18\u7684\u6cbb\u7597\uff0c\u56e0\u4e3a\u80bf\u7624\u5b66\u5bb6\u8fc7\u4e8e\u62c5\u5fc3\u5bf9\u5fc3\u810f\u9020\u6210\u6c38\u4e45\u6027\u635f\u4f24\u7684\u98ce\u9669\uff0c\u6240\u4ee5\u4ed6\u4eec\u4f1a\u7ed9\u60a3\u8005\u66f4\u4f4e\u6216\u66f4\u5c11\u5242\u91cf\u7684\u5316\u7597\u3002\u201d<\/p>\n

\u201c\u8fd9\u4e00\u53d1\u73b0\u4e5f\u53ef\u80fd\u4f1a\u5e26\u6765\u7684\u4e3b\u8981\u98ce\u9669(\u84bd\u73af\u9709\u7d20)\u6cbb\u7597,\u635f\u5bb3\u5fc3\u810f,\u53ef\u4ee5\u9884\u6d4b,\u751a\u81f3\u6709\u4e9b\u75c5\u4eba\u7ed9\u4e88\u4f4e\u5242\u91cf\u7684\u836f\u7269\u80fd\u627f\u53d7\u957f\u671f\u540e\u679c\u4e4b\u524d,\u533b\u751f\u4e0d\u77e5\u9053\u4ed6\u4eec\u662f\u5426\u4f1a\u53d1\u751f,\u201dTillett\u535a\u58eb\u8865\u5145\u8bf4\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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