{"id":445,"date":"2020-04-21T04:43:28","date_gmt":"2020-04-21T04:43:28","guid":{"rendered":"\/\/smallcapscn.x5view.co\/?p=445"},"modified":"2023-08-29T17:44:57","modified_gmt":"2023-08-29T17:44:57","slug":"noxopharm-plans-clinical-trial-take-the-sting-covid-19-deaths","status":"publish","type":"post","link":"https:\/\/smallcapscn.x5view.co\/?p=445","title":{"rendered":"Noxopharm\u516c\u53f8\u8ba1\u5212\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u963b\u6b62COVID19\u75c7\u72b6\u7684\u8fdb\u5c55"},"content":{"rendered":"<p>\u751f\u7269\u79d1\u6280\u516c\u53f8<a href=\"http:\/\/smallcaps-production.test\/stocks\/?lang=cn&#038;symbol=NOX\">Noxopharm (ASX:NOX)<\/a>\u5c06\u5bfb\u6c42\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40(FDA)\u7684\u6279\u51c6\uff0c\u5bf9\u5176\u665a\u671f\u524d\u5217\u817a\u764c\u836f\u7269\u7ef4\u5c24\u8fbe(Veyonda)\u7528\u4e8e\u65e9\u671fCOVID19\u60a3\u8005\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u76ee\u7684\u662f\u963b\u6b62\u75be\u75c5\u7684\u8fdb\u5c55\u3002<\/p>\n<p>Noxopharm\u516c\u53f8\u8ba4\u4e3a\uff0c\u8be5\u836f\u7684\u6d3b\u6027\u6210\u5206idroxonil\u53ef\u80fd\u4f1a\u963b\u6b62\u8d85\u708e\u75c7\uff0c\u8fd9\u79cd\u708e\u75c7\u88ab\u8ba4\u4e3a\u662f\u5bfc\u81f4COVID19\u611f\u67d3\u60a3\u8005\u6b7b\u4ea1\u7684\u539f\u56e0\u3002<\/p>\n<p>Idronoxil\u662f\u4e00\u79cd\u5177\u6709\u591a\u79cd\u6297\u764c\u673a\u5236\u7684\u5c0f\u5206\u5b50\u3002<\/p>\n<p>\u6291\u5236sphingosine-1-phosphate (S1P)\u548cSTING (\u5e72\u6270\u7d20\u57fa\u56e0\u7684\u523a\u6fc0\u7269)\u4fe1\u53f7\u901a\u8def\u88ab\u8ba4\u4e3a\u662f\u4e24\u5927\u4e3b\u8981\u56e0\u7d20\uff0c\u4e8c\u8005\u5728\u8c03\u8282\u80bf\u7624\u7684\u514d\u75ab\u548c\u708e\u75c7\u53cd\u5e94\u4e2d\u5747\u8d77\u5173\u952e\u4f5c\u7528\u3002<\/p>\n<h2>\u538b\u5012\u6027\u7684\u6761\u4ef6<\/h2>\n<p>COVID-19\u611f\u67d3\u7684\u5371\u9669\u5728\u4e8e\u5b83\u4ece\u4e00\u79cd\u8f7b\u5fae\u7684\u75be\u75c5\u53d1\u5c55\u4e3a\u4e00\u79cd\u4ee5\u547c\u5438\u548c\u591a\u5668\u5b98\u8870\u7aed\u3001\u51dd\u8840\u95ee\u9898\u548c\u611f\u67d3\u6027\u4f11\u514b\u4e3a\u7279\u5f81\u7684\u538b\u5012\u6027\u75be\u75c5\u3002<\/p>\n<p>\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u8fd9\u79cd\u75be\u75c5\u8fd8\u6ca1\u6709\u5f97\u5230\u6279\u51c6\u7684\u6cbb\u7597\uff0c\u75c5\u4eba\u7684\u6b7b\u4ea1\u7387\u4ecd\u7136\u5f88\u9ad8\u3002<\/p>\n<p>COVID-19\u672b\u671f\u7684\u533b\u7597\u5e72\u9884\u4ec5\u9650\u4e8e\u652f\u6301\u6027\u6cbb\u7597\uff0c\u5305\u62ec\u6297\u751f\u7d20\u548c\u547c\u5438\u673a\u7684\u4f7f\u7528\u3002<\/p>\n<h2>\u901a\u8def\u963b\u585e<\/h2>\n<p>Noxopharm\u516c\u53f8\u8ba1\u5212\u4f7f\u7528Veyonda\u6765\u963b\u65adSTING\u4fe1\u53f7\uff0c\u5728\u4e00\u4e9bCOVID-19\u60a3\u8005\u4e2d\uff0c\u8fd9\u79cd\u4fe1\u53f7\u88ab\u8ba4\u4e3a\u4f1a\u5bfc\u81f4\u4e3b\u8981\u5668\u5b98\u7684\u81ea\u6211\u6bc1\u706d\u3002<\/p>\n<p>\u8fd9\u4e00\u53d1\u73b0\u662f\u5728\u7ef4\u591a\u5229\u4e9a\u54c8\u5fb7\u900a\u533b\u5b66\u7814\u7a76\u6240\u7684\u7814\u7a76\u4e2d\u53d1\u73b0\u7684\uff0c\u8be5\u7814\u7a76\u8868\u660e\uff0cidronoxil\u53ef\u4ee5\u963b\u65ad\u4e0e\u4f4e\u6c27\u6c34\u5e73(\u6216\u7f3a\u6c27)\u5f15\u8d77\u7684\u7ec6\u80de\u635f\u4f24\u76f8\u5173\u7684STING\u4fe1\u53f7\u901a\u8def\u3002<\/p>\n<p>Noxopharm\u516c\u53f8\u9996\u5e2d\u6267\u884c\u5b98\u683cGraham Kelly\u8868\u793a\uff0c\u54c8\u5fb7\u900a\u7684\u7814\u7a76\u548c\u8ba1\u5212\u4e2d\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7684\u65f6\u673a\u9009\u62e9\u662f\u6b63\u786e\u7684\u3002<\/p>\n<p>\u4ed6\u8bf4:\u201c\u968f\u7740COVID-19\u6b7b\u4ea1\u7684\u4e00\u4e2a\u56e0\u7d20\u662f\u5f02\u5e38\u9ad8\u7684STING\u53cd\u5e94\u7684\u53ef\u80fd\u6027\u7684\u51fa\u73b0\uff0c\u5728[\u8fd9\u4e9b]\u60a3\u8005\u4e2d\u51c6\u5907\u6d4b\u8bd5STING\u4fe1\u53f7\u7684\u6291\u5236\u5242\u662f\u4e00\u4e2a\u76f8\u5f53\u5927\u7684\u8d23\u4efb\u3002\u201d<\/p>\n<p>\u201c\u8bc1\u660eVeyonda\u5bf9COVID-19\u60a3\u8005\u7684\u4ef7\u503c\u662f\u4e00\u4e2a\u6211\u4eec\u4e0d\u80fd\u5ffd\u89c6\u7684\u4eba\u9053\u4e3b\u4e49\u548c\u76d1\u7ba1\u6279\u51c6\u7684\u673a\u4f1a\u3002\u201d<\/p>\n<h2>STING\u7684\u5f71\u54cd<\/h2>\n<p>STING\u662f\u4eba\u7c7b\u4e00\u79cd\u539f\u59cb\u9632\u5fa1\u673a\u5236\u7684\u4e00\u90e8\u5206\uff0c\u5b83\u53ef\u4ee5\u63a2\u6d4b\u5230\u5165\u4fb5\u7684\u75c5\u539f\u751f\u7269(\u5982\u75c5\u6bd2\u6216\u7ec6\u83cc)\u7684\u5b58\u5728\uff0c\u5e76\u5728\u6e05\u9664\u53d7\u635f\u7684\u7ec6\u80de\u548c\u7ec4\u7ec7\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002<\/p>\n<p>\u8fd9\u4e24\u79cd\u53cd\u5e94\u90fd\u6d89\u53ca\u5230\u4e00\u79cd\u53eb\u505a\u7ec6\u80de\u56e0\u5b50\u7684\u86cb\u767d\u8d28\u7684\u4ea7\u751f\uff0c\u8fd9\u79cd\u86cb\u767d\u8d28\u80fd\u534f\u8c03\u968f\u540e\u7684\u514d\u75ab\u548c\u7ec4\u7ec7\u4fee\u590d(\u708e\u75c7)\u53cd\u5e94\u3002<\/p>\n<p>\u5728\u611f\u67d3\u7684\u65e9\u671f\u9636\u6bb5\uff0cSTING\u7684\u53c2\u4e0e\u53ef\u4ee5\u5bf9\u673a\u4f53\u5bf9\u67d0\u4e9b\u75c5\u539f\u4f53\u7684\u514d\u75ab\u53cd\u5e94\u4f5c\u51fa\u79ef\u6781\u7684\u8d21\u732e\u3002<\/p>\n<p>\u5982\u679c\u611f\u67d3\u6301\u7eed\u5e76\u53d1\u5c55\u5230\u9020\u6210\u5e7f\u6cdb\u7684\u7ec4\u7ec7\u635f\u4f24\u7684\u7a0b\u5ea6\uff0c\u5b83\u53ef\u80fd\u6210\u4e3a\u4e00\u79cd\u6d88\u6781\u7684\u548c\u81ea\u6bc1\u7684\u529b\u91cf\u3002<\/p>\n<p>\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0cSTING\u901a\u8def\u4f1a\u5f15\u53d1\u201c\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u201d\uff0c\u540c\u65f6\u4ea7\u751f\u51dd\u8840\u56e0\u5b50\uff0c\u6240\u6709\u8fd9\u4e9b\u90fd\u4f1a\u8fdb\u4e00\u6b65\u4fc3\u8fdb\u5668\u5b98\u635f\u4f24\u548c\u611f\u67d3\u6027\u4f11\u514b\u3002<\/p>\n<p>\u6839\u636e\u54c8\u5fb7\u900a\u7684\u7814\u7a76\uff0c\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u5f15\u53d1\u7684COVID-19\u60a3\u8005\u53ef\u56e0\u80ba\u529f\u80fd\u5dee\u5f15\u8d77\u7684\u7f3a\u6c27\u800c\u589e\u52a0\u7ec4\u7ec7\u635f\u4f24\u3002<\/p>\n<p>\u9ad8\u6c34\u5e73\u7684\u7ec6\u80de\u56e0\u5b50\u548c\u51dd\u8840\u56e0\u5b50\u88ab\u8bc1\u660e\u662f\u9884\u6d4b\u5176\u6b7b\u4ea1\u7387\u7684\u6307\u6807\u3002<\/p>\n<p>Kelly\u8bf4:\u201c\u9632\u6b62\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u73b0\u8c61\u548c(\u7531\u6b64\u4ea7\u751f\u7684)\u8113\u6bd2\u6027\u4f11\u514b\u5728covid19\u60a3\u8005\u4e2d\u53ef\u80fd\u4f1a\u6301\u7eed\u76f8\u5f53\u957f\u7684\u4e00\u6bb5\u65f6\u95f4\uff0c\u751a\u81f3\u53ef\u80fd\u4ecd\u7136\u662f\u4e00\u4e2a\u957f\u671f\u7684\u9700\u8981\uff0c\u5982\u679c\u5f00\u53d1\u4e00\u79cd\u6709\u6548\u7684\u75ab\u82d7\u88ab\u8bc1\u660e\u5177\u6709\u6311\u6218\u6027\u7684\u8bdd\u3002\u201d<\/p>\n<h2>\u80bf\u7624\u836f\u7269<\/h2>\n<p>Kelly\u8868\u793a\uff0cVeyonda\u9996\u5148\u662f\u4e00\u79cd\u80bf\u7624\u5b66\u836f\u7269\uff0c\u5176\u4e3b\u8981\u5173\u6ce8\u70b9\u4ecd\u662f<a href=\"http:\/\/smallcaps-production.test\/noxopharm-reports-positive-interim-clinical-trial-results-cancer-drug-veyonda\/?lang=cn\">\u7ec8\u672b\u671f\u524d\u5217\u817a\u764c<\/a>\u3002<\/p>\n<p>\u4ed6\u8868\u793a:\u201c\u4efb\u4f55\u9488\u5bf9\u975e\u80bf\u7624\u5b66\u60a3\u8005\u7684\u4e34\u5e8a\u7814\u7a76\u90fd\u5c06\u9700\u8981\u975e\u7a00\u91ca\u6027\u8d44\u91d1\uff0c(\u6211\u4eec)\u8ba4\u4e3a\uff0c\u5728\u5f53\u524d\u73af\u5883\u4e0b\uff0c\u4e00\u65e6\u6211\u4eec\u83b7\u5f97(\u8bd5\u9a8c)\u6279\u51c6\uff0c\u5c31\u5e94\u8be5\u80fd\u591f\u5b9e\u73b0\u8fd9\u4e00\u70b9\u3002\u201d<\/p>\n<p>\u201cVeyonda\u7684\u53e6\u4e00\u4e2a\u4f18\u52bf\u662f\uff0c\u5b83\u89e3\u51b3\u4e86\u5b89\u5168\u6027\u95ee\u9898\uff0c\u8bc1\u660e\u4e86\u5bf9\u665a\u671f\u764c\u75c7\u60a3\u8005\u548c\u751f\u6d3b\u8d28\u91cf\u8f83\u5dee\u7684\u60a3\u8005\u5177\u6709\u826f\u597d\u7684\u8010\u53d7\u6027\u3002\u201d<\/p>\n<p>Noxopharm\u76ee\u524d\u6b63\u5728\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\u5173\u4e8eCOVID-19\u60a3\u8005\u7684\u9002\u5f53\u76d1\u7ba1\u6279\u51c6\u9014\u5f84\u7684\u6307\u5bfc\u3002<\/p>\n<p>\u8be5\u516c\u53f8\u8fd8\u5728\u5bfb\u6c42\u4e00\u79cd\u9009\u62e9\uff0c\u5373\u5728\u906d\u53d7\u591a\u79cd\u611f\u67d3\u6e90\u611f\u67d3\u6027\u4f11\u514b\u7684\u60a3\u8005\u4e2d\u6d4b\u8bd5Veyonda\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u751f\u7269\u79d1\u6280\u516c\u53f8Noxopharm (ASX:NOX)\u5c06\u5bfb\u6c42\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40(FDA)\u7684\u6279\u51c6\uff0c\u5bf9\u5176\u665a\u671f\u524d\u5217\u817a\u764c\u836f\u7269\u7ef4\u5c24\u8fbe(Veyonda)\u7528\u4e8e\u65e9\u671fCOVID19\u60a3\u8005\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u76ee\u7684\u662f\u963b\u6b62\u75be\u75c5\u7684\u8fdb\u5c55\u3002 Noxopharm\u516c\u53f8\u8ba4\u4e3a\uff0c\u8be5\u836f\u7684\u6d3b\u6027\u6210\u5206idroxonil\u53ef\u80fd\u4f1a\u963b\u6b62\u8d85\u708e\u75c7\uff0c\u8fd9\u79cd\u708e\u75c7\u88ab\u8ba4\u4e3a\u662f\u5bfc\u81f4COVID19\u611f\u67d3\u60a3\u8005\u6b7b\u4ea1\u7684\u539f\u56e0\u3002 Idronoxil\u662f\u4e00\u79cd\u5177\u6709\u591a\u79cd\u6297\u764c\u673a\u5236\u7684\u5c0f\u5206\u5b50\u3002 \u6291\u5236sphingosine-1-phosphate (S1P)\u548cSTING (\u5e72\u6270\u7d20\u57fa\u56e0\u7684\u523a\u6fc0\u7269)\u4fe1\u53f7\u901a\u8def\u88ab\u8ba4\u4e3a\u662f\u4e24\u5927\u4e3b\u8981\u56e0\u7d20\uff0c\u4e8c\u8005\u5728\u8c03\u8282\u80bf\u7624\u7684\u514d\u75ab\u548c\u708e\u75c7\u53cd\u5e94\u4e2d\u5747\u8d77\u5173\u952e\u4f5c\u7528\u3002 \u538b\u5012\u6027\u7684\u6761\u4ef6 COVID-19\u611f\u67d3\u7684\u5371\u9669\u5728\u4e8e\u5b83\u4ece\u4e00\u79cd\u8f7b\u5fae\u7684\u75be\u75c5\u53d1\u5c55\u4e3a\u4e00\u79cd\u4ee5\u547c\u5438\u548c\u591a\u5668\u5b98\u8870\u7aed\u3001\u51dd\u8840\u95ee\u9898\u548c\u611f\u67d3\u6027\u4f11\u514b\u4e3a\u7279\u5f81\u7684\u538b\u5012\u6027\u75be\u75c5\u3002 \u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u8fd9\u79cd\u75be\u75c5\u8fd8\u6ca1\u6709\u5f97\u5230\u6279\u51c6\u7684\u6cbb\u7597\uff0c\u75c5\u4eba\u7684\u6b7b\u4ea1\u7387\u4ecd\u7136\u5f88\u9ad8\u3002 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