{"id":4651,"date":"2022-02-15T00:25:38","date_gmt":"2022-02-15T00:25:38","guid":{"rendered":"\/\/smallcapscn.x5view.co\/?p=4651"},"modified":"2023-08-29T17:52:58","modified_gmt":"2023-08-29T17:52:58","slug":"new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers","status":"publish","type":"post","link":"https:\/\/smallcapscn.x5view.co\/?p=4651","title":{"rendered":"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8"},"content":{"rendered":"

\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002<\/p>\n

\u5728\u57fa\u672c\u5c42\u9762\u4e0a\uff0cCAR-T\u6cbb\u7597\u5305\u62ec\u6536\u96c6\u548c\u4f7f\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7ec6\u80de\u6765\u6cbb\u7597\u4ed6\u4eec\u7684\u4e2a\u522b\u6076\u6027\u80bf\u7624\u3002<\/p>\n

CAR-T\u662f\u4e00\u79cd\u8fc7\u7ee7\u7ec6\u80de\u8f6c\u79fb\uff0c\u662f\u51e0\u79cd\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\u4e4b\u4e00\u3002\u7136\u800c\uff0cCAR-T\u662f\u6700\u5148\u8fdb\u7684\u3002<\/p>\n

2017\u5e74\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08US Food and Drug Administration\uff09\u6279\u51c6\u4e86\u4e24\u79cdCAR-T\u7ec6\u80de\u7597\u6cd5\u2014\u2014\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u53e6\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u665a\u671f\u6dcb\u5df4\u7624\u3002<\/p>\n

\u4f5c\u4e3aCAR-T\u7ec6\u80de\u9886\u57df\u7684\u65e9\u671f\u9886\u5bfc\u8005\uff0cRenier Brentjens\u535a\u58eb\u8bf4\u8fd9\u79cd\u7597\u6cd5\u76f8\u5f53\u4e8e\u7ed9\u75c5\u4eba\u4e00\u79cd\u201c\u6d3b\u7684\u836f\u7269\u201d\u3002<\/p>\n

\u76ee\u524dCAR-T\u6cbb\u7597\u7684\u652f\u67f1\u662fT\u7ec6\u80de\uff0c\u5b83\u901a\u5e38\u88ab\u79f0\u4e3a\u514d\u75ab\u7cfb\u7edf\u7684\u4e3b\u529b\u3002<\/p>\n

T\u7ec6\u80de\u5728\u534f\u8c03\u514d\u75ab\u53cd\u5e94\u548c\u6740\u6b7b\u88ab\u611f\u67d3\u7ec6\u80de\u65b9\u9762\u8d77\u7740\u5173\u952e\u4f5c\u7528\u3002<\/p>\n

\u6cbb\u7597\u5305\u62ec\u4ece\u75c5\u4eba\u8eab\u4e0a\u62bd\u53d6\u8840\u6db2\u548c\u63d0\u53d6T\u7ec6\u80de\u3002\u5229\u7528\u4e00\u79cd\u89e3\u9664\u6b66\u88c5\u7684\u75c5\u6bd2\uff0cT\u7ec6\u80de\u88ab\u6539\u9020\u6210\u5728\u5176\u8868\u9762\u4ea7\u751f\u5d4c\u5408\u6297\u539f\u53d7\u4f53(chimeric antigen receptors\uff1bCARs)\u3002<\/p>\n

\u6709\u524d\u9014\u7684\u65b0\u6570\u636e<\/h2>\n

Carl June\u6559\u6388\u9886\u5bfc\u4e86\u4e00\u7cfb\u5217\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u6d4b\u8bd5\u8fd9\u79cd\u7597\u6cd5\u2014\u2014\u4e3b\u8981\u662f\u5728\u767d\u8840\u75c5\u60a3\u8005\u8eab\u4e0a\u3002<\/p>\n

\u5728\u8bd5\u9a8c\u4e2d\uff0cCARs\u4f7fT\u7ec6\u80de\u80fd\u591f\u8bc6\u522b\u5e76\u9644\u7740\u5728\u80bf\u7624\u7ec6\u80de\u4e0a\u7684\u7279\u5b9a\u86cb\u767d\u8d28\u6216\u6297\u539f\u4e0a\u3002<\/p>\n

\u5728\u6cbb\u7597\u764c\u75c7\u65f6\uff0cT\u7ec6\u80de\u88ab\u8bbe\u8ba1\u6210\u8868\u8fbe\u6297\u539f\u7279\u5f02\u6027\u7684CAR\u3002\u8fd9\u4e9b\u6297\u539f\u7279\u5f02\u6027\u7684CAR\u5728\u5b9e\u9a8c\u5ba4\u91cc\u7e41\u6b96\u4e86\u6570\u4ebf\u4e2a\u3002<\/p>\n

June\u535a\u58eb\u548c\u4ed6\u7684\u540c\u4e8b\u6700\u8fd1\u5728\u300aNature\u300b\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u4e24\u540d10\u5e74\u524d\u63a5\u53d7CAR-T\u6cbb\u7597\u7684\u60a3\u8005\u7684\u6570\u636e\u548c\u8bc4\u8bba\u3002<\/p>\n

\u6570\u636e\u8868\u660e\uff0cCAR-T\u7ec6\u80de\u57282010\u5e74\u83b7\u5f97\u5b8c\u5168\u7f13\u89e3\u7684\u4e24\u540d\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u60a3\u8005\u4e2d10\u5e74\u540e\u4ecd\u7136\u6d3b\u8dc3\u3002<\/p>\n

Prescient\u8ba4\u4e3a\u8fd9\u4e00\u6570\u636e\u975e\u5e38\u9f13\u821e\u4eba\u5fc3\uff0c\u56e0\u4e3a\u5b83\u6709\u671b\u521b\u9020\u51fa\u4e0b\u4e00\u4ee3CAR-T\u7597\u6cd5\uff0c\u4e3a\u66f4\u591a\u7684\u6076\u6027\u80bf\u7624\u60a3\u8005\u5e26\u6765\u8fd9\u4e9b\u53cd\u5e94\u3002<\/p>\n

\u4e00\u4e2a\u6f5c\u5728\u7684\u6cbb\u7597?<\/h2>\n

\u5728\u8bc4\u8bba\u8fd9\u4e9b\u6570\u636e\u65f6\uff0cPrescient\u516c\u53f8\u7684\u8463\u4e8b\u603b\u7ecf\u7406\u517c\u9996\u5e2d\u6267\u884c\u5b98Steven Yatomi-Clarke\u8868\u793a\uff0c\u8be5\u516c\u53f8\u591a\u5e74\u6765\u4e00\u76f4\u5728\u201c\u9976\u6709\u5174\u8da3\u201d\u5730\u8ddf\u8e2a\u60a3\u8005\u7684\u7f13\u89e3\u60c5\u51b5\uff0c\u5c24\u5176\u662f\u968f\u7740\u7f13\u89e3\u65f6\u95f4\u201c\u8d8a\u6765\u8d8a\u957f\u201d\u3002<\/p>\n

\u201c\u6700\u8fd1\u771f\u6b63\u5438\u5f15\u4e16\u754c\u5404\u5730\u5934\u6761\u65b0\u95fb\u7684\u662fJune\u6559\u6388\u4f7f\u7528\u7684\u2018\u6cbb\u6108\u2019\u8fd9\u4e2a\u8bcd\uff0c\u201d\u4ed6\u8bf4\u3002<\/p>\n

\u8fd9\u4e2a\u672f\u8bed\u662f\u6709\u4e89\u8bae\u7684\uff0c\u56e0\u4e3a\u5b83\u4ee5\u524d\u4ece\u672a\u88ab\u7528\u4e8e\u764c\u75c7\u7684\u80cc\u666f\u4e0b\u3002<\/p>\n

\u76f8\u53cd\uff0c\u80bf\u7624\u5b66\u5bb6\u8bf4\u8981\u5ef6\u7f13\u75be\u75c5\u7684\u53d1\u5c55(\u6709\u65f6\u662f\u5c11\u91cf\u7684);\u5173\u4e8e\u63d0\u9ad8\u751f\u6d3b\u8d28\u91cf;\u751a\u81f3\u5728\u6cbb\u7597\u540e\u7684\u4e94\u5e74\u5185\u63d0\u9ad8\u751f\u5b58\u7387\u3002\u201d<\/p>\n

\u201c\u4f46\u6211\u4eec\u4e0d\u6562\u7528\u2018\u6cbb\u6108\u2019\u8fd9\u4e2a\u8bcd\uff0c\u201dYatomi-Clarke\u535a\u58eb\u89e3\u91ca\u9053\u3002<\/p>\n

\u4ed6\u8bf4\uff0c\u4f5c\u4e3a\u4e13\u5bb6\u7684June\u6559\u6388\u7684\u201c\u5de8\u5927\u7684\u7acb\u573a\u201d\uff0c\u201c\u6cbb\u6108\u201d\u7684\u5927\u80c6\u5ba3\u8a00\u5df2\u7ecf\u56de\u8361\u3002<\/p>\n

\u201c\u4ece\u6839\u672c\u4e0a\u770b\uff0c\u8fd9\u4e9b\u6536\u96c6\u4e86\u8d85\u8fc710\u5e74\u7684\u60ca\u4eba\u6570\u636e\uff0c\u5e76\u8bf4\uff0c\u2018\u5982\u679c\u5b83\u770b\u8d77\u6765\u50cf\u6cbb\u6108\uff0c\u95fb\u8d77\u6765\u50cf\u6cbb\u6108\u2019\uff0c\u6211\u4eec\u73b0\u5728\u53ef\u4ee5\u653e\u5fc3\u5730\u8bf4\uff0cCAR-T\u81f3\u5c11\u6709\u4e00\u4e9b\u6cbb\u7597\u767d\u8840\u75c5\u60a3\u8005\u7684\u6f5c\u529b\uff0c\u5c31\u50cf\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\u770b\u5230\u7684\u90a3\u4e9b\u3002\u201d<\/p>\n

\u53ea\u662f\u4e2a\u5f00\u59cb<\/h2>\n

Yatomi-Clarke\u6307\u51fa\uff0c\u8fd9\u53ea\u662fCAR-T\u6cbb\u7597\u7684\u5f00\u59cb\uff0c\u8fd9\u9879\u6280\u672f\u5df2\u7ecf\u670910\u5e74\u7684\u5386\u53f2\uff0c\u8fd9\u4e9b\u8bd5\u9a8c\u572810\u5e74\u524d\u5c31\u5f00\u59cb\u4e86\u3002<\/p>\n

“\u8fd9\u8ba9\u4f60\u60f3\u77e5\u9053\u8fd9\u4e0b\u4e00\u4ee3\uff0c\u4e5f\u5c31\u662fPrescient\u8d70\u5728\u524d\u5217\u7684\u90a3\u4e00\u4ee3\uff0c\u53ef\u80fd\u4f1a\u505a\u4ec0\u4e48”\u3002<\/p>\n

Yatomi-Clarke\u6307\u51fa\uff0cPrescient\u7684\u4e0b\u4e00\u4ee3\u6280\u672f\u4e5f\u6765\u81ea\u4e8e\u5f00\u521b\u539f\u59cb\u6280\u672f\u7684\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\uff08University of Pennsylvania\uff09\uff0c\u4ee5\u53ca\u725b\u6d25\u5927\u5b66\uff08Oxford University\uff09\u7684\u6295\u5165\u3002<\/p>\n

\u201c\u6211\u8ba4\u4e3a\u7b2c\u4e00\u6b21\u8fed\u4ee3\u5177\u6709\u6cbb\u7597\u6f5c\u529b\u662f\u975e\u5e38\u4ee4\u4eba\u5174\u594b\u7684\uff0c\u800c\u4e14\u53ea\u4f1a\u53d8\u5f97\u66f4\u597d\u3002\u5b83\u53ea\u4f1a\u8d8a\u6765\u8d8a\u4fbf\u5b9c\u3002\u201d<\/p>\n

\u73b0\u6709CAR-T\u7597\u6cd5\u7684\u969c\u788d<\/h2>\n

\u6839\u636eYatomi-Clarke\u7684\u8bf4\u6cd5\uff0c\u73b0\u6709CAR-T\u6cbb\u7597\u7684\u4e3b\u8981\u969c\u788d\u4e4b\u4e00\u662f\u6210\u672c\u548c\u5236\u9020\u65f6\u95f4\u7684\u957f\u5ea6\u3002<\/p>\n

\u201c\u76ee\u524d\uff0c\u5c3d\u7ba1CAR-T\u6280\u672f\u975e\u5e38\u51fa\u8272\uff0c\u4f46\u5b83\u975e\u5e38\u6602\u8d35\uff0c\u901f\u5ea6\u975e\u5e38\u6162\uff0c\u800c\u4e14\u5b58\u5728\u4e00\u4e9b\u5b89\u5168\u95ee\u9898\u3002\u201d<\/p>\n

\u4ed6\u8bf4\uff0c\u7531\u4e8e\u8fd9\u4e9b\u95ee\u9898\uff0c\u5b83\u53ea\u9002\u7528\u4e8e\u67d0\u4e9b\u8840\u764c\u548c\u5bf9\u5176\u4ed6\u6cbb\u7597\u65b9\u6848\u6709\u8010\u836f\u6027\u7684\u91cd\u75c5\u60a3\u8005\u3002<\/p>\n

\u76ee\u524dCAR-T\u5728\u8bb8\u591a\u5176\u4ed6\u764c\u75c7\u4e2d\u90fd\u6ca1\u6709\u53d1\u6325\u4f5c\u7528\uff0cYatomi-Clarke\u8bf4\u8fd9\u662f\u4e0b\u4e00\u4ee3\u6280\u672f\u7684\u201c\u5de8\u5927\u673a\u9047\u201d\u3002<\/p>\n

\u201c\u6211\u8ba4\u4e3a\uff0c\u6700\u7ec8\uff0c\u6574\u4e2a\u9886\u57df\u7684\u6700\u7ec8\u76ee\u6807\u662f\u6210\u4e3a\u4e00\u79cd\u73b0\u6210\u7684T\u7ec6\u80de\u6cbb\u7597\u65b9\u6cd5\u3002\u201d<\/p>\n

Yatomi-Clarke\u535a\u58eb\u8b66\u544a\u8bf4\uff0c\u8be5\u9886\u57df\u8ddd\u79bb\u73b0\u8d27\u4ea7\u54c1\u201c\u8fd8\u6709\u5f88\u957f\u7684\u8def\u8981\u8d70\u201d\u3002<\/p>\n

\u4e0b\u4e00\u4ee3OmniCAR\u7597\u6cd5<\/h2>\n

Prescient\u6b63\u8bd5\u56fe\u901a\u8fc7\u5176OmniCAR\u7597\u6cd5\u6765\u89e3\u51b3\u8fd9\u4e9b\u5173\u952e\u6311\u6218\u3002<\/p>\n

\u8be5\u516c\u53f8\u7684\u76ee\u6807\u662f\u4f7fCAR-T\u6cbb\u7597\u66f4\u6709\u6548\u3001\u66f4\u5b89\u5168\uff0c\u8fd9\u79cd\u6cbb\u7597\u65b9\u6cd5\u4e5f\u66f4\u5927\u89c4\u6a21\uff0c\u56e0\u6b64\u66f4\u4fbf\u5b9c\u3002<\/p>\n

\u201c\u56e0\u6b64\uff0c\u6211\u4eec\u53ef\u4ee5\u6cbb\u7597\u66f4\u591a\u7684\u764c\u75c7\uff0c\u63a5\u89e6\u5230\u66f4\u591a\u7684\u60a3\u8005\uff0c\u56e0\u4e3a\u6211\u4eec\u80fd\u591f\u964d\u4f4e\u6210\u672c\uff0c\u5236\u9020\u51fa\u66f4\u5b89\u5168\u3001\u66f4\u6709\u6548\u7684\u4ea7\u54c1\u3002\u201d<\/p>\n

\u201c\u51e0\u5e74\u524d\uff0c\u4eba\u4eec\u8fd8\u5728\u8c08\u8bba\u5f00\u53d1\u7eb3\u7c73\u673a\u5668\u4eba\uff0c\u8fd9\u79cd\u673a\u5668\u4eba\u53ef\u4ee5\u6ce8\u5c04\u5230\u4eba\u4f53\u5185\uff0c\u5e76\u5de1\u903b\u4f60\u7684\u8eab\u4f53\uff0c\u4ee5\u9632\u75be\u75c5\u548c\u764c\u75c7\u2014\u2014\u597d\u5427\uff0c\u8fd9\u5c31\u662f\u8fd9\u79cd(\u6cbb\u7597\u7684\u672c\u8d28)\u3002\u201d<\/p>\n

\u201c\u91cd\u65b0\u521b\u9020\u4e00\u4e2a\u5df2\u6709\u7684\u65b9\u6cd5? \u7ecf\u8fc730\u4ebf\u5e74\u7684\u8fdb\u5316\uff0c\u6211\u4eec\u7684\u8eab\u4f53\u6700\u7ec8\u4ea7\u751f\u4e86\u8fd9\u4e9b\u795e\u5947\u7684\u514d\u75ab\u7ec6\u80de\u2014\u2014\u6240\u4ee5\u53ea\u8981\u5229\u7528\u5b83\u4eec\u5c31\u53ef\u4ee5\u4e86\uff0c\u201d\u4ed6\u8865\u5145\u9053\u3002<\/p>\n

\u8be5\u516c\u53f8\u7684OmniCAR\u6280\u672f\u6709\u6f5c\u529b\u4ea7\u751f\u53ef\u63a7\u548c\u7075\u6d3b\u7684CAR-T\u4ea7\u54c1\uff0c\u7528\u4e8e\u6cbb\u7597\u5404\u79cd\u764c\u75c7\u3002<\/p>\n

\u8fd9\u4e9bCAR-T\u7ec6\u80de\u7597\u6cd5\u53ef\u4ee5\u5728\u8f93\u6ce8\u540e\u8fdb\u884c\u63a7\u5236\uff0c\u91cd\u65b0\u6b66\u88c5\u5e76\u4ece\u4e00\u79cd\u764c\u75c7\u6297\u539f\u91cd\u65b0\u5b9a\u5411\u5230\u53e6\u4e00\u79cd\u3002<\/p>\n

\u5728Prescient\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\uff0c\u8fd9\u4e9b\u4ea7\u54c1\u663e\u793a\u51fa\u6297\u764c\u6d3b\u6027\u548c\u9ad8\u6548\u529b\u3002<\/p>\n

\u7ed3\u679c\u663e\u793a\uff0cOmniCAR\u7ec6\u80de\u4e00\u65e6\u88ab\u6b66\u88c5\u8d77\u6765\uff0c\u5c31\u4f1a\u5728\u4f53\u5916\u5f00\u59cb\u6297\u539f\u76f4\u63a5\u6740\u4f24\u80bf\u7624\u7ec6\u80de\u3002<\/p>\n

\u7814\u7a76\u8fd8\u8868\u660e\uff0cOmniCAR\u7ec6\u80de\u53ef\u4ee5\u91cd\u65b0\u6b66\u88c5\uff0c\u7ee7\u7eed\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u800c\u4e0d\u4e27\u5931\u7ec6\u80de\u6bd2\u6027\uff0c\u800c\u4e14\u8fd9\u9879\u6280\u672f\u53ef\u4ee5\u7528\u4e8e\u5bf9\u6297\u591a\u79cd\u764c\u75c7\u6297\u539f\u3002<\/p>\n

\u5c55\u671b\u672a\u6765<\/h2>\n

\u5c55\u671b\u672a\u6765\u5341\u5e74\u8be5\u9886\u57df\u7684\u6280\u672f\u8fdb\u6b65\uff0cYatomi-Clarke\u8868\u793a\uff0c\u4ed6\u201c\u575a\u5b9a\u5730\u76f8\u4fe1\u201d\u5c06\u6709\u66f4\u591a\u764c\u75c7\u5f97\u5230\u66f4\u6210\u529f\u7684\u6cbb\u7597\u3002<\/p>\n

\u201c\u6211\u5e0c\u671bOmniCAR\u662f\u8fd9\u573a\u7ec6\u80de\u6cbb\u7597\u9769\u547d\u7684\u524d\u6cbf\u548c\u4e2d\u5fc3\uff0c\u56e0\u4e3a\u5b83\u662f\u4e0d\u53ef\u77e5\u8bba\u7684\uff0c\u53ef\u4ee5\u7528\u4e8e\u4efb\u4f55\u7c98\u5408\u5242\u548c\u4efb\u4f55\u7c7b\u578b\u7684\u514d\u75ab\u7ec6\u80de\u3002\u201d<\/p>\n

Yatomi-Clarke\u8868\u793a\uff0c\u4ed6\u8ba4\u4e3a\u672a\u6765\u5c06\u51fa\u73b0\u4e00\u4e2a\u201c\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\u7684\u751f\u6001\u7cfb\u7edf\u201d\u3002<\/p>\n

\u6837\u672c\u5c06\u4ece\u75c5\u4eba\u7684\u80bf\u7624\u4e2d\u63d0\u53d6\uff0c\u7136\u540e\u8fdb\u884c\u9274\u5b9a\u3002\u7136\u540e\uff0c\u533b\u751f\u5c06\u786e\u5b9a\u54ea\u79cd\u6d3b\u9875\u5939\u4e0e\u764c\u75c7\u76f8\u5339\u914d\u3002<\/p>\n

\u201c\u4ed6\u4eec\u53ef\u80fd\u4f1a\u8bf4\uff0c\u2018\u6839\u636e\u4f60\u7684\u764c\u75c7\u7279\u5f81\uff0c\u6211\u4eec\u9700\u8981OmniCAR\u7ed3\u5408\u52421\u30013\u548c10\u2019\uff0c\u7136\u540e\u628a\u5b83\u653e\u5728OmniCAR\u7ec6\u80de\u4e0a\u3002\u201d<\/p>\n

\u8fd9\u672c\u8d28\u4e0a\u662f\u4e00\u79cd\u9488\u5bf9\u7279\u5b9a\u60a3\u8005\u7684\u5b9a\u5236\u6cbb\u7597\uff0c\u800c\u4e14\u662f\u53ef\u63a7\u548c\u6709\u6548\u7684\u3002<\/p>\n

\u201c\u8fd9\u662f\u4e00\u79cd\u5373\u63d2\u5373\u7528\u7684\u6cbb\u7597\u764c\u75c7\u7684\u65b9\u6cd5\u3002\u4efb\u4f55\u62e5\u6709\u7c98\u5408\u5242\u6216\u7ec6\u80de\u7c7b\u578b\u7684\u4eba\u90fd\u53ef\u4ee5\u4e3a\u4ee5OmniCAR\u4e3a\u6838\u5fc3\u7684\u751f\u6001\u7cfb\u7edf\u505a\u51fa\u8d21\u732e\u3002\u201d<\/p>\n

\u8d85\u8d8a\u764c\u75c7\u7684\u9886\u57df<\/h2>\n

Yatomi-Clarke\u6307\u51fa\uff0c\u8fd9\u79cd\u6cbb\u7597\u65b9\u6cd5\u4e5f\u53ef\u4ee5\u5e94\u7528\u4e8e\u5176\u4ed6\u75be\u75c5\uff0c\u5305\u62ec\u611f\u67d3\u6027\u75be\u75c5\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u5982\u98ce\u6e7f\u6027\u5173\u8282\u708e\u3002<\/p>\n

\u201c\u5c31\u4eba\u4f53\u7684\u5de5\u4f5c\u65b9\u5f0f\u800c\u8a00\uff0c\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u662f\u764c\u75c7\u7684\u8fd1\u4eb2\u3002\u201d<\/p>\n

\u8fd9\u4e3aPrescient\u7684\u6280\u672f\u63d0\u4f9b\u4e86\u4e00\u4e2a\u6bd4\u764c\u75c7\u9886\u57df\u66f4\u5e7f\u9614\u7684\u5e02\u573a\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002 \u5728\u57fa\u672c\u5c42\u9762\u4e0a\uff0cCAR-T\u6cbb\u7597\u5305\u62ec\u6536\u96c6\u548c\u4f7f\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7ec6\u80de\u6765\u6cbb\u7597\u4ed6\u4eec\u7684\u4e2a\u522b\u6076\u6027\u80bf\u7624\u3002 CAR-T\u662f\u4e00\u79cd\u8fc7\u7ee7\u7ec6\u80de\u8f6c\u79fb\uff0c\u662f\u51e0\u79cd\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5\u4e4b\u4e00\u3002\u7136\u800c\uff0cCAR-T\u662f\u6700\u5148\u8fdb\u7684\u3002 2017\u5e74\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08US Food and Drug Administration\uff09\u6279\u51c6\u4e86\u4e24\u79cdCAR-T\u7ec6\u80de\u7597\u6cd5\u2014\u2014\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u513f\u7ae5\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u53e6\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u665a\u671f\u6dcb\u5df4\u7624\u3002 \u4f5c\u4e3aCAR-T\u7ec6\u80de\u9886\u57df\u7684\u65e9\u671f\u9886\u5bfc\u8005\uff0cRenier Brentjens\u535a\u58eb\u8bf4\u8fd9\u79cd\u7597\u6cd5\u76f8\u5f53\u4e8e\u7ed9\u75c5\u4eba\u4e00\u79cd\u201c\u6d3b\u7684\u836f\u7269\u201d\u3002 \u76ee\u524dCAR-T\u6cbb\u7597\u7684\u652f\u67f1\u662fT\u7ec6\u80de\uff0c\u5b83\u901a\u5e38\u88ab\u79f0\u4e3a\u514d\u75ab\u7cfb\u7edf\u7684\u4e3b\u529b\u3002 T\u7ec6\u80de\u5728\u534f\u8c03\u514d\u75ab\u53cd\u5e94\u548c\u6740\u6b7b\u88ab\u611f\u67d3\u7ec6\u80de\u65b9\u9762\u8d77\u7740\u5173\u952e\u4f5c\u7528\u3002 \u6cbb\u7597\u5305\u62ec\u4ece\u75c5\u4eba\u8eab\u4e0a\u62bd\u53d6\u8840\u6db2\u548c\u63d0\u53d6T\u7ec6\u80de\u3002\u5229\u7528\u4e00\u79cd\u89e3\u9664\u6b66\u88c5\u7684\u75c5\u6bd2\uff0cT\u7ec6\u80de\u88ab\u6539\u9020\u6210\u5728\u5176\u8868\u9762\u4ea7\u751f\u5d4c\u5408\u6297\u539f\u53d7\u4f53(chimeric antigen receptors\uff1bCARs)\u3002 \u6709\u524d\u9014\u7684\u65b0\u6570\u636e Carl June\u6559\u6388\u9886\u5bfc\u4e86\u4e00\u7cfb\u5217\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u6d4b\u8bd5\u8fd9\u79cd\u7597\u6cd5\u2014\u2014\u4e3b\u8981\u662f\u5728\u767d\u8840\u75c5\u60a3\u8005\u8eab\u4e0a\u3002 \u5728\u8bd5\u9a8c\u4e2d\uff0cCARs\u4f7fT\u7ec6\u80de\u80fd\u591f\u8bc6\u522b\u5e76\u9644\u7740\u5728\u80bf\u7624\u7ec6\u80de\u4e0a\u7684\u7279\u5b9a\u86cb\u767d\u8d28\u6216\u6297\u539f\u4e0a\u3002 \u5728\u6cbb\u7597\u764c\u75c7\u65f6\uff0cT\u7ec6\u80de\u88ab\u8bbe\u8ba1\u6210\u8868\u8fbe\u6297\u539f\u7279\u5f02\u6027\u7684CAR\u3002\u8fd9\u4e9b\u6297\u539f\u7279\u5f02\u6027\u7684CAR\u5728\u5b9e\u9a8c\u5ba4\u91cc\u7e41\u6b96\u4e86\u6570\u4ebf\u4e2a\u3002 June\u535a\u58eb\u548c\u4ed6\u7684\u540c\u4e8b\u6700\u8fd1\u5728\u300aNature\u300b\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u4e24\u540d10\u5e74\u524d\u63a5\u53d7CAR-T\u6cbb\u7597\u7684\u60a3\u8005\u7684\u6570\u636e\u548c\u8bc4\u8bba\u3002 \u6570\u636e\u8868\u660e\uff0cCAR-T\u7ec6\u80de\u57282010\u5e74\u83b7\u5f97\u5b8c\u5168\u7f13\u89e3\u7684\u4e24\u540d\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u60a3\u8005\u4e2d10\u5e74\u540e\u4ecd\u7136\u6d3b\u8dc3\u3002 Prescient\u8ba4\u4e3a\u8fd9\u4e00\u6570\u636e\u975e\u5e38\u9f13\u821e\u4eba\u5fc3\uff0c\u56e0\u4e3a\u5b83\u6709\u671b\u521b\u9020\u51fa\u4e0b\u4e00\u4ee3CAR-T\u7597\u6cd5\uff0c\u4e3a\u66f4\u591a\u7684\u6076\u6027\u80bf\u7624\u60a3\u8005\u5e26\u6765\u8fd9\u4e9b\u53cd\u5e94\u3002 \u4e00\u4e2a\u6f5c\u5728\u7684\u6cbb\u7597? \u5728\u8bc4\u8bba\u8fd9\u4e9b\u6570\u636e\u65f6\uff0cPrescient\u516c\u53f8\u7684\u8463\u4e8b\u603b\u7ecf\u7406\u517c\u9996\u5e2d\u6267\u884c\u5b98Steven Yatomi-Clarke\u8868\u793a\uff0c\u8be5\u516c\u53f8\u591a\u5e74\u6765\u4e00\u76f4\u5728\u201c\u9976\u6709\u5174\u8da3\u201d\u5730\u8ddf\u8e2a\u60a3\u8005\u7684\u7f13\u89e3\u60c5\u51b5\uff0c\u5c24\u5176\u662f\u968f\u7740\u7f13\u89e3\u65f6\u95f4\u201c\u8d8a\u6765\u8d8a\u957f\u201d\u3002 \u201c\u6700\u8fd1\u771f\u6b63\u5438\u5f15\u4e16\u754c\u5404\u5730\u5934\u6761\u65b0\u95fb\u7684\u662fJune\u6559\u6388\u4f7f\u7528\u7684\u2018\u6cbb\u6108\u2019\u8fd9\u4e2a\u8bcd\uff0c\u201d\u4ed6\u8bf4\u3002 \u8fd9\u4e2a\u672f\u8bed\u662f\u6709\u4e89\u8bae\u7684\uff0c\u56e0\u4e3a\u5b83\u4ee5\u524d\u4ece\u672a\u88ab\u7528\u4e8e\u764c\u75c7\u7684\u80cc\u666f\u4e0b\u3002 \u76f8\u53cd\uff0c\u80bf\u7624\u5b66\u5bb6\u8bf4\u8981\u5ef6\u7f13\u75be\u75c5\u7684\u53d1\u5c55(\u6709\u65f6\u662f\u5c11\u91cf\u7684);\u5173\u4e8e\u63d0\u9ad8\u751f\u6d3b\u8d28\u91cf;\u751a\u81f3\u5728\u6cbb\u7597\u540e\u7684\u4e94\u5e74\u5185\u63d0\u9ad8\u751f\u5b58\u7387\u3002\u201d \u201c\u4f46\u6211\u4eec\u4e0d\u6562\u7528\u2018\u6cbb\u6108\u2019\u8fd9\u4e2a\u8bcd\uff0c\u201dYatomi-Clarke\u535a\u58eb\u89e3\u91ca\u9053\u3002 \u4ed6\u8bf4\uff0c\u4f5c\u4e3a\u4e13\u5bb6\u7684June\u6559\u6388\u7684\u201c\u5de8\u5927\u7684\u7acb\u573a\u201d\uff0c\u201c\u6cbb\u6108\u201d\u7684\u5927\u80c6\u5ba3\u8a00\u5df2\u7ecf\u56de\u8361\u3002 \u201c\u4ece\u6839\u672c\u4e0a\u770b\uff0c\u8fd9\u4e9b\u6536\u96c6\u4e86\u8d85\u8fc710\u5e74\u7684\u60ca\u4eba\u6570\u636e\uff0c\u5e76\u8bf4\uff0c\u2018\u5982\u679c\u5b83\u770b\u8d77\u6765\u50cf\u6cbb\u6108\uff0c\u95fb\u8d77\u6765\u50cf\u6cbb\u6108\u2019\uff0c\u6211\u4eec\u73b0\u5728\u53ef\u4ee5\u653e\u5fc3\u5730\u8bf4\uff0cCAR-T\u81f3\u5c11\u6709\u4e00\u4e9b\u6cbb\u7597\u767d\u8840\u75c5\u60a3\u8005\u7684\u6f5c\u529b\uff0c\u5c31\u50cf\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\u770b\u5230\u7684\u90a3\u4e9b\u3002\u201d \u53ea\u662f\u4e2a\u5f00\u59cb Yatomi-Clarke\u6307\u51fa\uff0c\u8fd9\u53ea\u662fCAR-T\u6cbb\u7597\u7684\u5f00\u59cb\uff0c\u8fd9\u9879\u6280\u672f\u5df2\u7ecf\u670910\u5e74\u7684\u5386\u53f2\uff0c\u8fd9\u4e9b\u8bd5\u9a8c\u572810\u5e74\u524d\u5c31\u5f00\u59cb\u4e86\u3002 “\u8fd9\u8ba9\u4f60\u60f3\u77e5\u9053\u8fd9\u4e0b\u4e00\u4ee3\uff0c\u4e5f\u5c31\u662fPrescient\u8d70\u5728\u524d\u5217\u7684\u90a3\u4e00\u4ee3\uff0c\u53ef\u80fd\u4f1a\u505a\u4ec0\u4e48”\u3002 Yatomi-Clarke\u6307\u51fa\uff0cPrescient\u7684\u4e0b\u4e00\u4ee3\u6280\u672f\u4e5f\u6765\u81ea\u4e8e\u5f00\u521b\u539f\u59cb\u6280\u672f\u7684\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\uff08University of Pennsylvania\uff09\uff0c\u4ee5\u53ca\u725b\u6d25\u5927\u5b66\uff08Oxford University\uff09\u7684\u6295\u5165\u3002 \u201c\u6211\u8ba4\u4e3a\u7b2c\u4e00\u6b21\u8fed\u4ee3\u5177\u6709\u6cbb\u7597\u6f5c\u529b\u662f\u975e\u5e38\u4ee4\u4eba\u5174\u594b\u7684\uff0c\u800c\u4e14\u53ea\u4f1a\u53d8\u5f97\u66f4\u597d\u3002\u5b83\u53ea\u4f1a\u8d8a\u6765\u8d8a\u4fbf\u5b9c\u3002\u201d \u73b0\u6709CAR-T\u7597\u6cd5\u7684\u969c\u788d \u6839\u636eYatomi-Clarke\u7684\u8bf4\u6cd5\uff0c\u73b0\u6709CAR-T\u6cbb\u7597\u7684\u4e3b\u8981\u969c\u788d\u4e4b\u4e00\u662f\u6210\u672c\u548c\u5236\u9020\u65f6\u95f4\u7684\u957f\u5ea6\u3002 \u201c\u76ee\u524d\uff0c\u5c3d\u7ba1CAR-T\u6280\u672f\u975e\u5e38\u51fa\u8272\uff0c\u4f46\u5b83\u975e\u5e38\u6602\u8d35\uff0c\u901f\u5ea6\u975e\u5e38\u6162\uff0c\u800c\u4e14\u5b58\u5728\u4e00\u4e9b\u5b89\u5168\u95ee\u9898\u3002\u201d \u4ed6\u8bf4\uff0c\u7531\u4e8e\u8fd9\u4e9b\u95ee\u9898\uff0c\u5b83\u53ea\u9002\u7528\u4e8e\u67d0\u4e9b\u8840\u764c\u548c\u5bf9\u5176\u4ed6\u6cbb\u7597\u65b9\u6848\u6709\u8010\u836f\u6027\u7684\u91cd\u75c5\u60a3\u8005\u3002 \u76ee\u524dCAR-T\u5728\u8bb8\u591a\u5176\u4ed6\u764c\u75c7\u4e2d\u90fd\u6ca1\u6709\u53d1\u6325\u4f5c\u7528\uff0cYatomi-Clarke\u8bf4\u8fd9\u662f\u4e0b\u4e00\u4ee3\u6280\u672f\u7684\u201c\u5de8\u5927\u673a\u9047\u201d\u3002 \u201c\u6211\u8ba4\u4e3a\uff0c\u6700\u7ec8\uff0c\u6574\u4e2a\u9886\u57df\u7684\u6700\u7ec8\u76ee\u6807\u662f\u6210\u4e3a\u4e00\u79cd\u73b0\u6210\u7684T\u7ec6\u80de\u6cbb\u7597\u65b9\u6cd5\u3002\u201d Yatomi-Clarke\u535a\u58eb\u8b66\u544a\u8bf4\uff0c\u8be5\u9886\u57df\u8ddd\u79bb\u73b0\u8d27\u4ea7\u54c1\u201c\u8fd8\u6709\u5f88\u957f\u7684\u8def\u8981\u8d70\u201d\u3002 \u4e0b\u4e00\u4ee3OmniCAR\u7597\u6cd5 Prescient\u6b63\u8bd5\u56fe\u901a\u8fc7\u5176OmniCAR\u7597\u6cd5\u6765\u89e3\u51b3\u8fd9\u4e9b\u5173\u952e\u6311\u6218\u3002 \u8be5\u516c\u53f8\u7684\u76ee\u6807\u662f\u4f7fCAR-T\u6cbb\u7597\u66f4\u6709\u6548\u3001\u66f4\u5b89\u5168\uff0c\u8fd9\u79cd\u6cbb\u7597\u65b9\u6cd5\u4e5f\u66f4\u5927\u89c4\u6a21\uff0c\u56e0\u6b64\u66f4\u4fbf\u5b9c\u3002 \u201c\u56e0\u6b64\uff0c\u6211\u4eec\u53ef\u4ee5\u6cbb\u7597\u66f4\u591a\u7684\u764c\u75c7\uff0c\u63a5\u89e6\u5230\u66f4\u591a\u7684\u60a3\u8005\uff0c\u56e0\u4e3a\u6211\u4eec\u80fd\u591f\u964d\u4f4e\u6210\u672c\uff0c\u5236\u9020\u51fa\u66f4\u5b89\u5168\u3001\u66f4\u6709\u6548\u7684\u4ea7\u54c1\u3002\u201d \u201c\u51e0\u5e74\u524d\uff0c\u4eba\u4eec\u8fd8\u5728\u8c08\u8bba\u5f00\u53d1\u7eb3\u7c73\u673a\u5668\u4eba\uff0c\u8fd9\u79cd\u673a\u5668\u4eba\u53ef\u4ee5\u6ce8\u5c04\u5230\u4eba\u4f53\u5185\uff0c\u5e76\u5de1\u903b\u4f60\u7684\u8eab\u4f53\uff0c\u4ee5\u9632\u75be\u75c5\u548c\u764c\u75c7\u2014\u2014\u597d\u5427\uff0c\u8fd9\u5c31\u662f\u8fd9\u79cd(\u6cbb\u7597\u7684\u672c\u8d28)\u3002\u201d… Continue reading \u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":18724,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[171],"yoast_head":"\n\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8<\/title>\n<meta name=\"description\" content=\"\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8\" \/>\n<meta property=\"og:description\" content=\"\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002\" \/>\n<meta property=\"og:url\" content=\"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/\" \/>\n<meta property=\"og:site_name\" content=\"smallcapsCN\" \/>\n<meta property=\"article:published_time\" content=\"2022-02-15T00:25:38+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-29T17:52:58+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/smallcapscn.x5view.co\/wp-content\/uploads\/2023\/08\/Prescient-Therapeutics-PTX-ASX-next-generation-CAR-T-cell-therapy-cancer.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Lorna Nicholas\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lorna Nicholas\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/\",\"url\":\"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/\",\"name\":\"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8\",\"isPartOf\":{\"@id\":\"https:\/\/smallcapscn.x5view.co\/#website\"},\"datePublished\":\"2022-02-15T00:25:38+00:00\",\"dateModified\":\"2023-08-29T17:52:58+00:00\",\"author\":{\"@id\":\"https:\/\/smallcapscn.x5view.co\/#\/schema\/person\/3e816860d3443582b1918467347eeb60\"},\"description\":\"\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002\",\"breadcrumb\":{\"@id\":\"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/smallcapscn.x5view.co\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/smallcapscn.x5view.co\/#website\",\"url\":\"https:\/\/smallcapscn.x5view.co\/\",\"name\":\"smallcapsCN\",\"description\":\"Just another WordPress site\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/smallcapscn.x5view.co\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/smallcapscn.x5view.co\/#\/schema\/person\/3e816860d3443582b1918467347eeb60\",\"name\":\"Lorna Nicholas\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/smallcapscn.x5view.co\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/431dd83ad861252293034fed39d5d7a5?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/431dd83ad861252293034fed39d5d7a5?s=96&d=mm&r=g\",\"caption\":\"Lorna Nicholas\"},\"description\":\"Lorna has more than 15 years' experience as a business\/finance journalist and editor. She has written for numerous industry publications reporting on various sectors, including: resources, energy, construction, biotech, pharma, science and technology, agriculture, and chemicals. Specialising in resources, Lorna has also covered a myriad of small and large cap ASX and dual-listed stocks.\",\"url\":\"https:\/\/smallcapscn.x5view.co\/?author=3\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8","description":"\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002","robots":{"index":"noindex","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"og_locale":"en_US","og_type":"article","og_title":"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8","og_description":"\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002","og_url":"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/","og_site_name":"smallcapsCN","article_published_time":"2022-02-15T00:25:38+00:00","article_modified_time":"2023-08-29T17:52:58+00:00","og_image":[{"width":640,"height":400,"url":"https:\/\/smallcapscn.x5view.co\/wp-content\/uploads\/2023\/08\/Prescient-Therapeutics-PTX-ASX-next-generation-CAR-T-cell-therapy-cancer.jpg","type":"image\/jpeg"}],"author":"Lorna Nicholas","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Lorna Nicholas"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/","url":"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/","name":"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8","isPartOf":{"@id":"https:\/\/smallcapscn.x5view.co\/#website"},"datePublished":"2022-02-15T00:25:38+00:00","dateModified":"2023-08-29T17:52:58+00:00","author":{"@id":"https:\/\/smallcapscn.x5view.co\/#\/schema\/person\/3e816860d3443582b1918467347eeb60"},"description":"\u53d1\u8868\u5728\u79d1\u5b66\u6742\u5fd7\u300aNature\u300b\u4e0a\u7684\u65b0\u6570\u636e\u652f\u6301\u4e86\u4e34\u5e8a\u9636\u6bb5\u80bf\u7624\u516c\u53f8Prescient Therapeutics (ASX: PTX)\u4f7f\u7528\u4e0b\u4e00\u4ee3\u7ec6\u80de\u6cbb\u7597\u5e73\u53f0OmniCAR\uff0c\u8be5\u5e73\u53f0\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7684\u514d\u75ab\u7cfb\u7edf\u6765\u5bf9\u6297\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u3002","breadcrumb":{"@id":"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/smallcapscn.x5view.co\/new-data-prescient-therapeutics-next-generation-car-t-cell-therapy-cancers\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/smallcapscn.x5view.co\/"},{"@type":"ListItem","position":2,"name":"\u65b0\u7684\u6570\u636e\u652f\u6301\u4e86Prescient Therapeutics\u5bf9\u4e0b\u4e00\u4ee3CAR-T\u7ec6\u80de\u6cbb\u7597\u764c\u75c7\u7684\u5173\u6ce8"}]},{"@type":"WebSite","@id":"https:\/\/smallcapscn.x5view.co\/#website","url":"https:\/\/smallcapscn.x5view.co\/","name":"smallcapsCN","description":"Just another WordPress site","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/smallcapscn.x5view.co\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/smallcapscn.x5view.co\/#\/schema\/person\/3e816860d3443582b1918467347eeb60","name":"Lorna Nicholas","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/smallcapscn.x5view.co\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/431dd83ad861252293034fed39d5d7a5?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/431dd83ad861252293034fed39d5d7a5?s=96&d=mm&r=g","caption":"Lorna Nicholas"},"description":"Lorna has more than 15 years' experience as a business\/finance journalist and editor. She has written for numerous industry publications reporting on various sectors, including: resources, energy, construction, biotech, pharma, science and technology, agriculture, and chemicals. Specialising in resources, Lorna has also covered a myriad of small and large cap ASX and dual-listed stocks.","url":"https:\/\/smallcapscn.x5view.co\/?author=3"}]}},"_links":{"self":[{"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=\/wp\/v2\/posts\/4651"}],"collection":[{"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4651"}],"version-history":[{"count":1,"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=\/wp\/v2\/posts\/4651\/revisions"}],"predecessor-version":[{"id":14530,"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=\/wp\/v2\/posts\/4651\/revisions\/14530"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=\/wp\/v2\/media\/18724"}],"wp:attachment":[{"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4651"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/smallcapscn.x5view.co\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}