{"id":6706,"date":"2023-04-20T01:51:32","date_gmt":"2023-04-20T01:51:32","guid":{"rendered":"\/\/smallcapscn.x5view.co\/?p=6706"},"modified":"2023-08-29T17:57:39","modified_gmt":"2023-08-29T17:57:39","slug":"imugene-positive-imaging-data-oncolytic-virotherapy-candidate-checkvacc","status":"publish","type":"post","link":"https:\/\/smallcapscn.x5view.co\/?p=6706","title":{"rendered":"Imugene\u663e\u793a\u6eb6\u7624\u75c5\u6bd2\u6cbb\u7597\u5019\u9009\u836f\u7269CHECKvacc\u7684\u9633\u6027\u6210\u50cf\u6570\u636e"},"content":{"rendered":"

\u4e34\u5e8a\u9636\u6bb5\u514d\u75ab\u80bf\u7624\u5b66\u516c\u53f8Imugene (ASX: IMU)\u516c\u5e03\u4e86\u5176\u6eb6\u7624\u75c5\u6bd2\u6cbb\u7597\u5019\u9009\u836f\u7269CHECKvacc\u6cbb\u7597\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\u7684\u9633\u6027\u6210\u50cf\u6570\u636e\u3002<\/p>\n

\u5e0c\u671b\u4e4b\u57ce\u7684 Jamie Rand \u535a\u58eb\u662f\u5916\u79d1\u90e8\u95e8\u4e73\u817a\u5916\u79d1\u7684\u52a9\u7406\u6559\u6388\uff0c\u4ed6\u5728\u672c\u5468\u4e8e\u4f5b\u7f57\u91cc\u8fbe\u5dde\u4e3e\u884c\u7684American Association for Cancer Research (AACR) 2023\u5e74\u5e74\u4f1a\u4e0a\u5c55\u793a\u4e86\u8fd9\u4e9b\u6570\u636e\u3002<\/p>\n

\u521d\u6b65\u6210\u50cf\u6570\u636e\u663e\u793a\uff0c\u57281\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e09\u4e2a\u961f\u5217\u4e2d\uff0cCHECKvacc (\u4e5f\u79f0\u4e3aCF33-hNIS-antiPDL1) \u5728\u6240\u6709\u4e09\u79cd\u5242\u91cf\u6c34\u5e73\u4e0b\u90fd\u5177\u6709\u201c\u826f\u597d\u7684\u8010\u53d7\u6027\u201d\u3002<\/p>\n

CHECKvacc\u662f\u4e00\u79cd\u6b66\u88c5\u5d4c\u5408\u75d8\u75d8\u75c5\u6bd2(\u6eb6\u7624\u75c5\u6bd2)\uff0c\u88ab\u8bbe\u8ba1\u7528\u6765\u9009\u62e9\u6027\u5730\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\uff0c\u540c\u65f6\u4e5f\u6fc0\u6d3b\u514d\u75ab\u7cfb\u7edf\u3002<\/p>\n

\u5728\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\u60a3\u8005\u76841\u671f\u8bd5\u9a8c\u4e2d\uff0cCHECKvacc\u9776\u5411PD-L1\u86cb\u767d\u5e76\u6fc0\u6d3b\u5c40\u90e8\u80bf\u7624\u5fae\u73af\u5883\u3002<\/p>\n

SPECT\u6210\u50cf\u7ed3\u679c<\/h2>\n

\u5728\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\u60a3\u8005\u8eab\u4e0a\u5b8c\u6210\u4e86SPECT(\u5355\u5149\u5b50\u53d1\u5c04\u8ba1\u7b97\u673a\u65ad\u5c42\u626b\u63cf)\u6210\u50cf\uff0c\u8be5\u6570\u636e\u5728\u4f5b\u7f57\u91cc\u8fbe\u4f1a\u8bae\u4e0a\u516c\u5e03\u3002<\/p>\n

\u901a\u8fc7\u7624\u5185\u6ce8\u5c04(IT)\u63a5\u53d7CHECKvacc\u6cbb\u7597\u7684\u672c\u75c5\u60a3\u8005\u8fdb\u884cSPECT\u6210\u50cf\u3002<\/p>\n

\u5728\u8fd9\u4e2a\u4f8b\u5b50\u4e2d\uff0c75%\u901a\u8fc7IT\u6ce8\u5c04\u63a5\u53d7CHECKvacc\u6ce8\u5c04\u7684\u4e73\u817a\u764c\u75c5\u53d8\u663e\u793a\u589e\u5f3a\u3002<\/p>\n

Imugene\u6307\u51fa\uff0c\u8fd9\u8868\u660e\u5c40\u90e8\u75c5\u6bd2\u590d\u5236\u4ea7\u751fhNIS(\u4eba\u7898\u5316\u94a0\u540c\u8f6c\u8fd0\u4f53)\u8868\u8fbe\u3002<\/p>\n

hNIS\u5141\u8bb8Imugene\u5728\u6cbb\u7597\u671f\u95f4\u901a\u8fc7SPECT\u5b9e\u65f6\u8ffd\u8e2a\u75c5\u6bd2\u590d\u5236\u7684\u4f4d\u7f6e\u3002<\/p>\n

\u8fd9\u4e9b\u60a3\u8005\u7684SPECT\u6210\u50cf\u663e\u793a\uff0c\u4e0e\u6591\u9a73\u7684\u771f\u76ae\u8f6c\u79fb\u76f8\u6bd4\uff0c\u76ae\u4e0b\u7ed3\u8282\u3001\u808c\u8089\u5185\u7ed3\u8282\u548c\u6dcb\u5df4\u7ed3\u7684\u589e\u5f3a\u6709\u6240\u6539\u5584\u3002<\/p>\n

\u8fdb\u4e00\u6b65\u5206\u6790<\/h2>\n

Imugene\u8463\u4e8b\u603b\u7ecf\u7406\u517c\u9996\u5e2d\u6267\u884c\u5b98 Leslie Chong \u535a\u58eb\u8868\u793a\uff0c\u201c\u5f88\u9ad8\u5174\u201d\u786e\u8ba4CHECKvacc\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u3002<\/p>\n

\u5979\u6307\u51fa\uff0c\u6210\u50cf\u6570\u636e\u663e\u793a\u4e86CHECKvacc\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u7684\u201c\u5176\u4ed6\u51e0\u4e2a\u79ef\u6781\u7ed3\u679c\u201d\u3002<\/p>\n

\u201c\u6211\u4eec\u5c06\u5b8c\u6210\u5bf9\u6570\u636e\u7684\u8fdb\u4e00\u6b65\u5206\u6790\uff0c\u5e76\u671f\u5f85\u8bd5\u9a8c\u7ee7\u7eed\u8fdb\u884c\uff0c\u4ee5\u671f\u6539\u5584\u60a3\u8005\u9009\u62e9\u6709\u9650\u7684\u764c\u75c7\u7684\u9884\u540e\uff0c\u201dChong\u535a\u58eb\u8865\u5145\u8bf4\u3002<\/p>\n

\u68c0\u67e5\u75ab\u82d7\u548c\u6eb6\u7624\u75c5\u6bd2<\/h2>\n

CHECKvacc\u6765\u81eaCF33\u53d1\u660e\u4eba Yuman Fong \u6559\u6388\u7684\u5b9e\u9a8c\u5ba4\uff0cYuman Fong \u6559\u6388\u662fCity of Hope \u7684\u00a0Sangiacomo Family Chair \u7684 Surgical Oncology \u4e3b\u5e2d\u3002<\/p>\n

Fong \u6559\u6388\u662f\u6eb6\u7624\u75c5\u6bd2\u9886\u57df\u7684\u77e5\u540d\u4e13\u5bb6\u3002<\/p>\n

\u5728\u9009\u62e9\u6027\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\u7684\u540c\u65f6\uff0c\u6eb6\u7624\u75c5\u6bd2\u6fc0\u6d3b\u7cfb\u7edf\u518d\u6b21\u5bf9\u6297\u764c\u7ec6\u80de\uff0c\u8fd9\u4e24\u79cd\u884c\u4e3a\u90fd\u6709\u53ef\u80fd\u6539\u5584\u4e34\u5e8a\u53cd\u5e94\u548c\u751f\u5b58\u7387\u3002<\/p>\n

\u5728\u4e09\u9634\u6027\u4e73\u817a\u764c\u5f02\u79cd\u79fb\u690d\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\uff0cCHECKvacc\u5df2\u7ecf\u8bc1\u660e\u4e86\u201c\u5f3a\u5927\u7684\u6297\u764c\u6d3b\u6027\u201d\u3002<\/p>\n

\u4e09\u9634\u6027\u4e73\u817a\u764c<\/h2>\n

\u4e34\u5e8a\u524d\u8bd5\u9a8c\u8868\u660e\uff0cCHECKvacc\u68c0\u6d4b\u5e76\u5b89\u5168\u6740\u6b7b\u4e09\u9634\u6027\u4e73\u817a\u764c\u7684\u5242\u91cf\u6bd4\u76ee\u524d\u6b63\u5728\u4e34\u5e8a\u7814\u7a76\u7684\u5176\u4ed6\u6eb6\u7624\u75c5\u6bd2\u201c\u4f4e\u51e0\u4e2a\u6570\u91cf\u7ea7\u201d\u3002<\/p>\n

\u4e09\u9634\u6027\u4e73\u817a\u764c\u662f\u4e73\u817a\u764c\u7684\u4e00\u79cd\u4e9a\u578b\uff0c\u7ea6\u5360\u6240\u6709\u4e73\u817a\u764c\u75c5\u4f8b\u768420%\u3002<\/p>\n

\u5b83\u7684\u4e2d\u4f4d\u751f\u5b58\u671f\u4e3a12\u4e2a\u6708\uff0c\u76ee\u524d\u5bf9\u8fd9\u79cd\u75be\u75c5\u5df2\u7ecf\u6269\u6563\u7684\u60a3\u8005\u6ca1\u6709\u6709\u6548\u7684\u9776\u5411\u6cbb\u7597\u3002<\/p>\n

\u6b64\u5916\uff0c\u4e09\u9634\u6027\u4e73\u817a\u764c\u4f1a\u8fc5\u901f\u5bf9\u5316\u7597\u4ea7\u751f\u8010\u836f\u6027\u3002<\/p>\n

\u56e0\u6b64\uff0cChong\u535a\u58eb\u8bf4\uff0c\u201c\u8feb\u5207\u9700\u8981\u201d\u6cbb\u7597\u8fd9\u79cd\u75be\u75c5\u7684\u65b0\u7597\u6cd5\u6765\u6539\u5584\u4e34\u5e8a\u7ed3\u679c\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e34\u5e8a\u9636\u6bb5\u514d\u75ab\u80bf\u7624\u5b66\u516c\u53f8Imugene (ASX: IMU)\u516c\u5e03\u4e86\u5176\u6eb6\u7624\u75c5\u6bd2\u6cbb\u7597\u5019\u9009\u836f\u7269CHECKvacc\u6cbb\u7597\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\u7684\u9633\u6027\u6210\u50cf\u6570\u636e\u3002 \u5e0c\u671b\u4e4b\u57ce\u7684 Jamie Rand \u535a\u58eb\u662f\u5916\u79d1\u90e8\u95e8\u4e73\u817a\u5916\u79d1\u7684\u52a9\u7406\u6559\u6388\uff0c\u4ed6\u5728\u672c\u5468\u4e8e\u4f5b\u7f57\u91cc\u8fbe\u5dde\u4e3e\u884c\u7684American Association for Cancer Research (AACR) 2023\u5e74\u5e74\u4f1a\u4e0a\u5c55\u793a\u4e86\u8fd9\u4e9b\u6570\u636e\u3002 \u521d\u6b65\u6210\u50cf\u6570\u636e\u663e\u793a\uff0c\u57281\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e09\u4e2a\u961f\u5217\u4e2d\uff0cCHECKvacc (\u4e5f\u79f0\u4e3aCF33-hNIS-antiPDL1) \u5728\u6240\u6709\u4e09\u79cd\u5242\u91cf\u6c34\u5e73\u4e0b\u90fd\u5177\u6709\u201c\u826f\u597d\u7684\u8010\u53d7\u6027\u201d\u3002 CHECKvacc\u662f\u4e00\u79cd\u6b66\u88c5\u5d4c\u5408\u75d8\u75d8\u75c5\u6bd2(\u6eb6\u7624\u75c5\u6bd2)\uff0c\u88ab\u8bbe\u8ba1\u7528\u6765\u9009\u62e9\u6027\u5730\u6740\u6b7b\u80bf\u7624\u7ec6\u80de\uff0c\u540c\u65f6\u4e5f\u6fc0\u6d3b\u514d\u75ab\u7cfb\u7edf\u3002 \u5728\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\u60a3\u8005\u76841\u671f\u8bd5\u9a8c\u4e2d\uff0cCHECKvacc\u9776\u5411PD-L1\u86cb\u767d\u5e76\u6fc0\u6d3b\u5c40\u90e8\u80bf\u7624\u5fae\u73af\u5883\u3002 SPECT\u6210\u50cf\u7ed3\u679c \u5728\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\u60a3\u8005\u8eab\u4e0a\u5b8c\u6210\u4e86SPECT(\u5355\u5149\u5b50\u53d1\u5c04\u8ba1\u7b97\u673a\u65ad\u5c42\u626b\u63cf)\u6210\u50cf\uff0c\u8be5\u6570\u636e\u5728\u4f5b\u7f57\u91cc\u8fbe\u4f1a\u8bae\u4e0a\u516c\u5e03\u3002 \u901a\u8fc7\u7624\u5185\u6ce8\u5c04(IT)\u63a5\u53d7CHECKvacc\u6cbb\u7597\u7684\u672c\u75c5\u60a3\u8005\u8fdb\u884cSPECT\u6210\u50cf\u3002 \u5728\u8fd9\u4e2a\u4f8b\u5b50\u4e2d\uff0c75%\u901a\u8fc7IT\u6ce8\u5c04\u63a5\u53d7CHECKvacc\u6ce8\u5c04\u7684\u4e73\u817a\u764c\u75c5\u53d8\u663e\u793a\u589e\u5f3a\u3002 Imugene\u6307\u51fa\uff0c\u8fd9\u8868\u660e\u5c40\u90e8\u75c5\u6bd2\u590d\u5236\u4ea7\u751fhNIS(\u4eba\u7898\u5316\u94a0\u540c\u8f6c\u8fd0\u4f53)\u8868\u8fbe\u3002 hNIS\u5141\u8bb8Imugene\u5728\u6cbb\u7597\u671f\u95f4\u901a\u8fc7SPECT\u5b9e\u65f6\u8ffd\u8e2a\u75c5\u6bd2\u590d\u5236\u7684\u4f4d\u7f6e\u3002 \u8fd9\u4e9b\u60a3\u8005\u7684SPECT\u6210\u50cf\u663e\u793a\uff0c\u4e0e\u6591\u9a73\u7684\u771f\u76ae\u8f6c\u79fb\u76f8\u6bd4\uff0c\u76ae\u4e0b\u7ed3\u8282\u3001\u808c\u8089\u5185\u7ed3\u8282\u548c\u6dcb\u5df4\u7ed3\u7684\u589e\u5f3a\u6709\u6240\u6539\u5584\u3002 \u8fdb\u4e00\u6b65\u5206\u6790 Imugene\u8463\u4e8b\u603b\u7ecf\u7406\u517c\u9996\u5e2d\u6267\u884c\u5b98 Leslie Chong \u535a\u58eb\u8868\u793a\uff0c\u201c\u5f88\u9ad8\u5174\u201d\u786e\u8ba4CHECKvacc\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u3002 \u5979\u6307\u51fa\uff0c\u6210\u50cf\u6570\u636e\u663e\u793a\u4e86CHECKvacc\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u7684\u201c\u5176\u4ed6\u51e0\u4e2a\u79ef\u6781\u7ed3\u679c\u201d\u3002 \u201c\u6211\u4eec\u5c06\u5b8c\u6210\u5bf9\u6570\u636e\u7684\u8fdb\u4e00\u6b65\u5206\u6790\uff0c\u5e76\u671f\u5f85\u8bd5\u9a8c\u7ee7\u7eed\u8fdb\u884c\uff0c\u4ee5\u671f\u6539\u5584\u60a3\u8005\u9009\u62e9\u6709\u9650\u7684\u764c\u75c7\u7684\u9884\u540e\uff0c\u201dChong\u535a\u58eb\u8865\u5145\u8bf4\u3002 \u68c0\u67e5\u75ab\u82d7\u548c\u6eb6\u7624\u75c5\u6bd2 CHECKvacc\u6765\u81eaCF33\u53d1\u660e\u4eba Yuman Fong \u6559\u6388\u7684\u5b9e\u9a8c\u5ba4\uff0cYuman Fong \u6559\u6388\u662fCity of Hope \u7684\u00a0Sangiacomo Family Chair \u7684 Surgical Oncology \u4e3b\u5e2d\u3002 Fong \u6559\u6388\u662f\u6eb6\u7624\u75c5\u6bd2\u9886\u57df\u7684\u77e5\u540d\u4e13\u5bb6\u3002 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