{"id":95,"date":"2020-03-23T23:48:28","date_gmt":"2020-03-23T23:48:28","guid":{"rendered":"\/\/smallcapscn.x5view.co\/?p=95"},"modified":"2023-08-29T18:02:09","modified_gmt":"2023-08-29T18:02:09","slug":"paradigm-doses-all-trial-patients-zilosul-while-dodging-covid-19-impact","status":"publish","type":"post","link":"https:\/\/smallcapscn.x5view.co\/?p=95","title":{"rendered":"Paradigm\u7ed9\u6240\u6709\u8bd5\u9a8c\u60a3\u8005\u6ce8\u5c04Zilosul\uff0c\u540c\u65f6\u907f\u5f00COVID-19\u7684\u5f71\u54cd"},"content":{"rendered":"

\u7531Paradigm Biopharmaceuticals (ASX: PAR)\uff0c Zilosul\u516c\u53f8\u5f00\u53d1\u7684\u4e00\u79cd\u5b9e\u9a8c\u6027\u7684\u819d\u5173\u8282\u9aa8\u6027\u5173\u8282\u708e\u6cbb\u7597\u836f\u7269\uff0c\u73b0\u5728\u5df2\u7ecf\u5728\u7f8e\u56fdFDA\u6279\u51c6\u7684\u6269\u5927\u4f7f\u7528(\u4e5f\u88ab\u79f0\u4e3a\u6148\u60b2\u4f7f\u7528)\u8ba1\u5212\u7684\u6240\u670910\u540d\u60a3\u8005\u4e2d\u4f7f\u7528\u4e86\u836f\u7269\u3002<\/p>\n

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\u5728\u8c08\u5230COVID-19\u7684\u5f71\u54cd\u65f6\uff0cParadigm\u8868\u793a:\u201c\u516c\u53f8\u8ba4\u4e3a\uff0c\u76ee\u524dCOVID-19\u5bf9\u6574\u4e2a\u4e1a\u52a1\u8fd0\u8425\u7684\u5f71\u54cd\u5e76\u4e0d\u5927\uff0c\u56e0\u4e3a\u76ee\u524d\u8fd8\u6ca1\u6709\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u800c\u4e14\u5927\u591a\u6570\u516c\u53f8\u5458\u5de5\u90fd\u5df2\u7ecf\u5728\u8fdc\u7a0b\u529e\u516c\u3002\u201d<\/p>\n

\u8fdb\u53d6<\/h2>\n

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\u5728FDA\u9879\u76ee\u4e0b\u63a5\u53d7\u6cbb\u7597\u768410\u540d\u60a3\u8005\u5747\u672a\u80fd\u4ece\u5176\u4ed6\u5404\u79cd\u819d\u5173\u8282\u9aa8\u6027\u5173\u8282\u708e\u6cbb\u7597\u4e2d\u83b7\u76ca\uff0c\u8fc4\u4eca\u4e3a\u6b62\uff0c\u4ed6\u4eec\u5bf9Zilosul\u7684\u65e9\u671f\u7597\u6548\u63d0\u4f9b\u4e86\u79ef\u6781\u7684\u53cd\u9988\u3002<\/p>\n

\u201c\u4f5c\u4e3a\u4e00\u4e2a\u524d\u7f8e\u56fd\u56fd\u5bb6\u6a44\u6984\u7403\u8054\u76df\u4e13\u4e1a\u548c\u73b0\u5728\u6d3b\u8dc3\u7684\u6821\u53cb,\u6211\u906d\u53d7\u4e86OA(\u9aa8\u5173\u8282\u708e)\u56e0\u4e3a\u5728\u6211\u73a9\u51e0\u5929,\u4e86\u89e3\u7b2c\u4e00\u624b\u7684\u8870\u5f31\u6548\u5e94\u5982\u4f55\u5f71\u54cd\u4e00\u4e2a\u4eba\u7684\u751f\u6d3b,\u201d\u6258\u9a6c\u65af\u00b7\u57c3\u5f17\u96f7\u7279(Thomas Everett)\u8bf4,\u524dNFL\u5b89\u5168\u548c\u4e24\u5c4a\u8d85\u7ea7\u7897\u51a0\u519b,\u76ee\u524dFDA\u8ba1\u5212\u4e0b\u63a5\u53d7\u6cbb\u7597\u3002<\/p>\n

\u4ed6\u8bf4:\u201c\u6211\u5c1d\u8bd5\u4e86\u51e0\u4e4e\u6240\u6709\u7684\u4f20\u7edf\u6cbb\u7597\u65b9\u6cd5\uff0c\u4f46\u90fd\u6ca1\u6709\u53d6\u5f97\u5f88\u5927\u7684\u6210\u529f\uff0c\u6240\u4ee5\u6211\u975e\u5e38\u6fc0\u52a8\uff0c\u975e\u5e38\u9ad8\u5174\u80fd\u53c2\u4e0e\u8fd9\u9879\u7814\u7a76\uff0c\u5b83\u4e0d\u4ec5\u80fd\u6cbb\u7597\u75c7\u72b6\uff0c\u8fd8\u80fd\u6cbb\u7597\u6f5c\u5728\u7684\u75be\u75c5\u3002\u201d<\/p>\n

\u8be5\u9879\u76ee\u7684\u53e6\u4e00\u4f4d\u60a3\u8005\u7406\u67e5\u5fb7\u00b7\u8303\u00b7\u5fb7\u9c81\u6ed5(Richard Van Druten)\u66fe\u662f\u582a\u8428\u65af\u57ce\u7684\u51a0\u519b\uff0c\u4ed6\u5ba3\u79f0\u81ea\u5df1\u201c\u6700\u8fd1\u5f00\u59cb\u8212\u670d\u5730\u8d70\u8def\uff0c\u751a\u81f3\u662f\u591a\u5e74\u6765\u7b2c\u4e00\u6b21\u6162\u8dd1\u201d\u3002<\/p>\n

\u6765\u81ea\u7f8e\u56fd\u65e9\u671f\u60a3\u8005\u7684\u8f76\u4e8b\u8bc1\u636e\u548c\u6765\u81eaAFL\u8fd0\u52a8\u5458\u7684\u9633\u6027\u62a5\u544a\u8868\u660e\uff0cZilosul\u53ef\u80fd\u6210\u4e3a\u4e00\u79cd\u5728\u5168\u7403\u9500\u552e\u7684\u5177\u6709\u5546\u4e1a\u53ef\u884c\u6027\u7684\u836f\u7269\u3002<\/p>\n

\u5728\u8fc7\u53bb\u7684\u7814\u7a76\u4e2d\uff0c\u8303\u683c\u7684\u836f\u7269\u51cf\u5c11\u4e8684.4%\u7684\u60a3\u8005\u7684\u5173\u8282\u75bc\u75db\u548c\u6539\u5584\u4e86\u819d\u5173\u8282\u529f\u80fd\uff0c\u8fd9\u662f\u8be5\u516c\u53f8\u5728\u6fb3\u5927\u5229\u4e9a\u7ecftga\u6279\u51c6\u7684\u7279\u6b8a\u8bbf\u95ee\u8ba1\u5212\u7684\u4e00\u90e8\u5206\u3002<\/p>\n

\u6839\u636e\u8303\u578b\uff0c\u9879\u76ee\u4e2d\u7684\u6bcf\u4e2a\u60a3\u8005\u90fd\u8fdb\u884c\u4e86\u7b5b\u9009\u548c\u8bc4\u4f30\uff0c\u4ee5\u6d4b\u91cf\u4ed6\u4eec\u7684\u57fa\u7ebf\u75bc\u75db\u8bc4\u5206\uff0c\u5305\u62ec\u8be6\u7ec6\u7684MRI\u626b\u63cf\uff0c\u4ee5\u786e\u5b9a\u819d\u5173\u8282\u5185\u662f\u5426\u5b58\u5728\u9aa8\u9ad3\u6c34\u80bf\u75c5\u53d8(BMEL)\u3002<\/p>\n

\u9aa8\u9ad3\u6c34\u80bf\u7684\u53d1\u751f\u662f\u7531\u4e8e\u9aa8\u9ad3\u4e2d\u6db2\u4f53\u7684\u79ef\u805a\uff0c\u8fd9\u5f80\u5f80\u662f\u5bf9\u9aa8\u6298\u7b49\u635f\u4f24\u6216\u9aa8\u5173\u8282\u708e\u7b49\u60c5\u51b5\u7684\u53cd\u5e94\u3002<\/p>\n

\u8303\u8303\u5f0f\u8ba1\u5212\u5728\u6cbb\u7597\u5b8c\u62106\u5468\u540e\u8fdb\u884c\u968f\u8bbf\u626b\u63cf\u548c\u75bc\u75db\u6d4b\u91cf\uff0c\u7136\u540e\u57282020\u5e74\u7b2c\u4e09\u5b63\u5ea6\u62a5\u544a\u7ed3\u679c\u3002<\/p>\n

Paradigm Biopharmaceuticals\u9996\u5e2d\u6267\u884c\u5b98\u4fdd\u7f57\u2022\u96f7\u5c3c(Paul Rennie)\u8868\u793a:\u201c\u968f\u7740\u60a3\u8005\u5728\u6cbb\u7597\u5468\u671f\u4e2d\u7684\u8fdb\u5c55\uff0c\u6211\u4eec\u7ee7\u7eed\u53d7\u5230\u6bcf\u4f4d\u60a3\u8005\u53cd\u9988\u7684\u9f13\u821e\uff0c\u5e76\u671f\u5f85\u7740\u4e00\u65e6\u6709\u5e02\u573a\uff0c\u5c31\u80fd\u5c06\u7ed3\u679c\u5448\u73b0\u7ed9\u5e02\u573a\u3002\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

\u7531Paradigm Biopharmaceuticals (ASX: PAR)\uff0c Zilosul\u516c\u53f8\u5f00\u53d1\u7684\u4e00\u79cd\u5b9e\u9a8c\u6027\u7684\u819d\u5173\u8282\u9aa8\u6027\u5173\u8282\u708e\u6cbb\u7597\u836f\u7269\uff0c\u73b0\u5728\u5df2\u7ecf\u5728\u7f8e\u56fdFDA\u6279\u51c6\u7684\u6269\u5927\u4f7f\u7528(\u4e5f\u88ab\u79f0\u4e3a\u6148\u60b2\u4f7f\u7528)\u8ba1\u5212\u7684\u6240\u670910\u540d\u60a3\u8005\u4e2d\u4f7f\u7528\u4e86\u836f\u7269\u3002 \u8303\u683c\u5728\u7ed9\u6295\u8d44\u8005\u7684\u4e00\u4efd\u58f0\u660e\u4e2d\u8bf4\uff0c\u6b63\u5728\u63a5\u53d7\u6cbb\u7597\u7684\u75c5\u4eba\u5904\u4e8e\u6cbb\u7597\u5468\u671f\u7684\u4e0d\u540c\u9636\u6bb5\uff0c\u6700\u540e\u4e00\u4f4d\u63a5\u53d7\u6cbb\u7597\u7684\u75c5\u4eba\u6628\u5929\u521a\u521a\u63a5\u53d7\u4e86\u6700\u540e\u4e00\u6b21\u6cbb\u7597\u3002 \u91cd\u8981\u7684\u662f\uff0c\u8be5\u516c\u53f8\u5411\u6295\u8d44\u8005\u548c\u5e02\u573a\u5206\u6790\u5e08\u4fdd\u8bc1\uff0c\u5b83\u7684\u9879\u76ee\u201c\u4e0d\u53d7\u201d\u6301\u7eed\u7684COVID-19\u5927\u6d41\u884c\u7684\u5f71\u54cd\uff0c\u4ece\u800c\u907f\u514d\u5728\u75c5\u4eba\u548c\u516c\u53f8\u7684\u65e5\u7a0b\u5b89\u6392\u4e0a\u51fa\u73b0\u5012\u9000\u3002 \u5728\u8c08\u5230COVID-19\u7684\u5f71\u54cd\u65f6\uff0cParadigm\u8868\u793a:\u201c\u516c\u53f8\u8ba4\u4e3a\uff0c\u76ee\u524dCOVID-19\u5bf9\u6574\u4e2a\u4e1a\u52a1\u8fd0\u8425\u7684\u5f71\u54cd\u5e76\u4e0d\u5927\uff0c\u56e0\u4e3a\u76ee\u524d\u8fd8\u6ca1\u6709\u8fdb\u884c\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u800c\u4e14\u5927\u591a\u6570\u516c\u53f8\u5458\u5de5\u90fd\u5df2\u7ecf\u5728\u8fdc\u7a0b\u529e\u516c\u3002\u201d \u8fdb\u53d6 \u8303\u578b\u89c4\u5b9a\uff0c\u5b83\u6b63\u5728\u79ef\u6781\u76d1\u6d4b\u6bcf\u4e2a\u75c5\u4eba\u7684\u8fdb\u5c55\uff0c\u5e76\u6ce8\u610f\u5230\u75c5\u4eba\u5728\u63a5\u53d7\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u201c\u4e00\u81f4\u7684\u79ef\u6781\u53cd\u9988\u201d\u3002 \u5728FDA\u9879\u76ee\u4e0b\u63a5\u53d7\u6cbb\u7597\u768410\u540d\u60a3\u8005\u5747\u672a\u80fd\u4ece\u5176\u4ed6\u5404\u79cd\u819d\u5173\u8282\u9aa8\u6027\u5173\u8282\u708e\u6cbb\u7597\u4e2d\u83b7\u76ca\uff0c\u8fc4\u4eca\u4e3a\u6b62\uff0c\u4ed6\u4eec\u5bf9Zilosul\u7684\u65e9\u671f\u7597\u6548\u63d0\u4f9b\u4e86\u79ef\u6781\u7684\u53cd\u9988\u3002 \u201c\u4f5c\u4e3a\u4e00\u4e2a\u524d\u7f8e\u56fd\u56fd\u5bb6\u6a44\u6984\u7403\u8054\u76df\u4e13\u4e1a\u548c\u73b0\u5728\u6d3b\u8dc3\u7684\u6821\u53cb,\u6211\u906d\u53d7\u4e86OA(\u9aa8\u5173\u8282\u708e)\u56e0\u4e3a\u5728\u6211\u73a9\u51e0\u5929,\u4e86\u89e3\u7b2c\u4e00\u624b\u7684\u8870\u5f31\u6548\u5e94\u5982\u4f55\u5f71\u54cd\u4e00\u4e2a\u4eba\u7684\u751f\u6d3b,\u201d\u6258\u9a6c\u65af\u00b7\u57c3\u5f17\u96f7\u7279(Thomas Everett)\u8bf4,\u524dNFL\u5b89\u5168\u548c\u4e24\u5c4a\u8d85\u7ea7\u7897\u51a0\u519b,\u76ee\u524dFDA\u8ba1\u5212\u4e0b\u63a5\u53d7\u6cbb\u7597\u3002 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